Disruption of VEGF Mediated Flk-1 Signaling Leads to a Gradual Loss of Vessel Health and Cardiac Function During Myocardial Infarction: Potential Therapy With Pellino-1.

Thirunavukkarasu, Mahesh; Selvaraju, Vaithinathan; Joshi, Mandip; Coca-Soliz, Vladimir; Tapias, Leonidas; Saad, IbnalWalid; Fournier, Craig; Husain, Aaftab; Campbell, Jacob; Yee, Siu-Pok; Sanchez, Juan A; Palesty, J Alexander; McFadden, David W; Maulik, Nilanjana

Disruption of VEGF Mediated Flk-1 Signaling Leads to a Gradual Loss of Vessel Health and Cardiac Function During Myocardial Infarction: Potential Therapy With Pellino-1.

Thirunavukkarasu, Mahesh; Selvaraju, Vaithinathan; Joshi, Mandip; Coca-Soliz, Vladimir; Tapias, Leonidas; Saad, IbnalWalid; Fournier, Craig; Husain, Aaftab; Campbell, Jacob; Yee, Siu-Pok; Sanchez, Juan A; Palesty, J Alexander; McFadden, David W; Maulik, Nilanjana.

Afiliación

Thirunavukkarasu M; 1 Molecular Cardiology and Angiogenesis Laboratory University of Connecticut Health Farmington CT.
Selvaraju V; 2 Department of Surgery University of Connecticut Health Farmington CT.
Joshi M; 1 Molecular Cardiology and Angiogenesis Laboratory University of Connecticut Health Farmington CT.
Coca-Soliz V; 2 Department of Surgery University of Connecticut Health Farmington CT.
Tapias L; 1 Molecular Cardiology and Angiogenesis Laboratory University of Connecticut Health Farmington CT.
Saad I; 3 Stanley J. Dudrick Department of Surgery Saint Mary's Hospital Waterbury CT.
Fournier C; 1 Molecular Cardiology and Angiogenesis Laboratory University of Connecticut Health Farmington CT.
Husain A; 3 Stanley J. Dudrick Department of Surgery Saint Mary's Hospital Waterbury CT.
Campbell J; 1 Molecular Cardiology and Angiogenesis Laboratory University of Connecticut Health Farmington CT.
Yee SP; 3 Stanley J. Dudrick Department of Surgery Saint Mary's Hospital Waterbury CT.
Sanchez JA; 1 Molecular Cardiology and Angiogenesis Laboratory University of Connecticut Health Farmington CT.
Palesty JA; 3 Stanley J. Dudrick Department of Surgery Saint Mary's Hospital Waterbury CT.
McFadden DW; 1 Molecular Cardiology and Angiogenesis Laboratory University of Connecticut Health Farmington CT.
Maulik N; 2 Department of Surgery University of Connecticut Health Farmington CT.

J Am Heart Assoc ; 7(18): e007601, 2018 09 18.

Article en En | MEDLINE | ID: mdl-30371196

Asunto(s)

Terapia Genética/métodos; Infarto del Miocardio/terapia; Proteínas Nucleares/farmacología; Ubiquitina-Proteína Ligasas/farmacología; Receptor 2 de Factores de Crecimiento Endotelial Vascular/metabolismo; Animales; Western Blotting; Células Cultivadas; Modelos Animales de Enfermedad; Regulación de la Expresión Génica; Humanos; Inmunohistoquímica; Ratones; Ratones Endogámicos ICR; Infarto del Miocardio/genética; Infarto del Miocardio/metabolismo; Miocardio/metabolismo; Miocardio/patología; Neovascularización Fisiológica/efectos de los fármacos; Proteínas Nucleares/biosíntesis; Proteínas Nucleares/genética; Fosforilación; Transducción de Señal; Ubiquitina-Proteína Ligasas/biosíntesis; Ubiquitina-Proteína Ligasas/genética

Palabras clave

adenovirus; animal models; gene therapy; genetics; myocardial infarction; myocardial revascularization

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Terapia Genética / Receptor 2 de Factores de Crecimiento Endotelial Vascular / Ubiquitina-Proteína Ligasas / Infarto del Miocardio Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Am Heart Assoc Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google