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Methicillin-resistant staphylococcus aureus pneumonia in older people: a diagnostic and therapeutic challenge.
Kiselinova, M; Velghe, A; Piers, R; Verhasselt, B; Van Den Noortgate, N.
Afiliación
  • Kiselinova M; Department of Internal Medicine, University Hospital Ghent , Ghent , Belgium.
  • Velghe A; Department of Geriatric Medicine, University Hospital Ghent , Ghent , Belgium.
  • Piers R; Department of Internal Medicine, University Hospital Ghent , Ghent , Belgium.
  • Verhasselt B; Department of Geriatric Medicine, University Hospital Ghent , Ghent , Belgium.
  • Van Den Noortgate N; Department of Internal Medicine, University Hospital Ghent , Ghent , Belgium.
Acta Clin Belg ; 74(6): 456-459, 2019 Dec.
Article en En | MEDLINE | ID: mdl-30444192
Pneumonia is one of the leading causes of death in older people, with high mortality rates (> 80%). One of the bacterial pathogens causing pneumonia is Staphylococcus aureus. The unique adaptive ability of S. aureus to a broad range of antibiotics has led to the emergence of methicillin-resistant S. aureus (MRSA) strain. MRSA pneumonia remains a relatively uncommon infection in older people, but it is associated with a very high mortality rate. We report two cases of MRSA pneumonia that highlight the severe clinical presentation and virulence of MRSA infections in geriatric population. MRSA pneumonia can present with mostly an uncontrollable clinical evolution and an infaust prognosis. Therefore, clinicians should be aware of MRSA pneumonia in patients with comorbidities, recent hospitalization with antibiotic treatment, previous MRSA infections and also in patients residing in nursing homes/revalidation centers. Low prevalence of MRSA combined with a lack of highly distinctive clinical features makes accurate targeting of empirical treatment with antibiotics very difficult. Currently, monotherapy with linezolid or vancomycin remain the first choice, in adult patients with proven MRSA infection. Despite the higher age related mortality rates, there are no specific treatment guidelines for older patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumonía Estafilocócica / Vancomicina / Infección Hospitalaria / Staphylococcus aureus Resistente a Meticilina Tipo de estudio: Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Aged80 / Humans / Male Idioma: En Revista: Acta Clin Belg Año: 2019 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumonía Estafilocócica / Vancomicina / Infección Hospitalaria / Staphylococcus aureus Resistente a Meticilina Tipo de estudio: Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Aged80 / Humans / Male Idioma: En Revista: Acta Clin Belg Año: 2019 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Reino Unido