Significance of 1 kHz Pure-tone Threshold in Acute Low-frequency Sensorineural Hearing Loss.
Otol Neurotol
; 39(10): e950-e955, 2018 12.
Article
en En
| MEDLINE
| ID: mdl-30444841
ABSTRACT
OBJECTIVES:
To analyze risk factors for acute low-frequency hearing loss (ALFHL), and compare treatment outcomes in the presence or absence of such risk factors. STUDYDESIGN:
A case series featuring retrospective chart review.SETTING:
An academic university hospital. PATIENTS We included 170 ALFHL patients without vertigo. All of the patients received one of four treatments low-dose steroid (LD-steroid), high-dose steroid (HD-steroid), LD-steroid and diuretics (LD-combination therapy), and ITDI (intratympanic dexamethasone injection) and diuretics (ITDI-combination therapy). To identify risk factors, we reviewed the clinical features of patients such as age, sex, chief complaint, accompanying symptoms, diabetes, hypertension, time from disease onset, the extent of hearing loss, treatment methods, and 1âkHz involvement.INTERVENTIONS:
ALFHL was diagnosed based on the average hearing loss >30âdB at 250 and 500âHz.RESULTS:
The overall rates of hearing recovery were 70-80% in the four treatment groups. In terms of the prognosis of ALFHL patients, we found that a longer time from disease onset and 1âkHz involvement were independent risk factors for poor prognosis. In addition, we compared treatment outcomes of four treatment methods in the presence or absence of risk factors. In ALFHL patients with risk factors, we found statistically significant differences (pâ=â0.042) among treatment methods; effectiveness ranged in the order if ITDI-combination therapy, LD-combination therapy, HD-steroid, and LD-steroid.CONCLUSIONS:
Risk factors for poor hearing recovery in ALFHL included longer symptom duration and 1âkHz involvement. In ALFHL with such risk factors, combination therapy was more effective than oral steroid therapy.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Umbral Auditivo
/
Dexametasona
/
Glucocorticoides
/
Pérdida Auditiva Sensorineural
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Otol Neurotol
Asunto de la revista:
NEUROLOGIA
/
OTORRINOLARINGOLOGIA
Año:
2018
Tipo del documento:
Article