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DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.
He, Yizhou Joseph; Meghani, Khyati; Caron, Marie-Christine; Yang, Chunyu; Ronato, Daryl A; Bian, Jie; Sharma, Anchal; Moore, Jessica; Niraj, Joshi; Detappe, Alexandre; Doench, John G; Legube, Gaelle; Root, David E; D'Andrea, Alan D; Drané, Pascal; De, Subhajyoti; Konstantinopoulos, Panagiotis A; Masson, Jean-Yves; Chowdhury, Dipanjan.
Afiliación
  • He YJ; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Meghani K; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Caron MC; Genome Stability Laboratory, CHU de Québec Research Center, HDQ Pavilion, Oncology Axis, Québec City, Québec, Canada.
  • Yang C; Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, Québec City, Québec, Canada.
  • Ronato DA; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Bian J; Genome Stability Laboratory, CHU de Québec Research Center, HDQ Pavilion, Oncology Axis, Québec City, Québec, Canada.
  • Sharma A; Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University Cancer Research Center, Québec City, Québec, Canada.
  • Moore J; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Niraj J; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Detappe A; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Doench JG; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Legube G; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Root DE; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • D'Andrea AD; LBCMCP, Centre de Biologie Integrative (CBI), CNRS, Université de Toulouse, UT3, Toulouse, France.
  • Drané P; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • De S; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Konstantinopoulos PA; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Masson JY; Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Chowdhury D; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
Nature ; 563(7732): 522-526, 2018 11.
Article en En | MEDLINE | ID: mdl-30464262
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Proteína BRCA1 / Genes BRCA1 / Dineínas Citoplasmáticas / Reparación del ADN por Recombinación / Proteína Homóloga de MRE11 Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Nature Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Proteína BRCA1 / Genes BRCA1 / Dineínas Citoplasmáticas / Reparación del ADN por Recombinación / Proteína Homóloga de MRE11 Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Nature Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos