Pharmaceutical significance of azepane based motifs for drug discovery: A critical review.

Zha, Gao-Feng; Rakesh, K P; Manukumar, H M; Shantharam, C S; Long, Sihui

Zha, Gao-Feng; Rakesh, K P; Manukumar, H M; Shantharam, C S; Long, Sihui.

Afiliación

Zha GF; Key Laboratory for Green Chemical Process of Ministry of Education, Hubie Key Laboratory of Novel Reactor and Green Chemical Technology, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, 206 Optics Valley 1st Rd, East Lake New Technology Development District, Wuhan, Hubei,
Rakesh KP; Department of Pharmaceutical Engineering, School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan, 430070, China. Electronic address: rakeshasg@gmail.com.
Manukumar HM; Department of Studies in Biotechnology, University of Mysore, Manasagangotri, Mysuru, 570006, Karnataka, India.
Shantharam CS; Department of Chemistry, Pooja Bhagavath Memorial Mahajana Education Centre, Mysuru, 570016, Karnataka, India.
Long S; Key Laboratory for Green Chemical Process of Ministry of Education, Hubie Key Laboratory of Novel Reactor and Green Chemical Technology, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, 206 Optics Valley 1st Rd, East Lake New Technology Development District, Wuhan, Hubei,

Eur J Med Chem ; 162: 465-494, 2019 Jan 15.

Article en En | MEDLINE | ID: mdl-30469042

Asunto(s)

Compuestos Aza/uso terapéutico; Química Farmacéutica; Descubrimiento de Drogas; Animales; Humanos; Simulación del Acoplamiento Molecular; Relación Estructura-Actividad

Palabras clave

Azepane; Biological activities; Drug discovery; SAR

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos Aza / Química Farmacéutica / Descubrimiento de Drogas Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article Pais de publicación: Francia

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