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Metastasis of adenoid cystic carcinoma from a submandibular gland to the larynx.
Ishikawa, Tomohiko; Tateda, Masaru; Oshima, Hidetoshi; Sawada, Akari; Oka, Naomi; Suzuki, Hiroyoshi; Hashimoto, Sho.
Afiliación
  • Ishikawa T; Department of Otolaryngology - Head and Neck Surgery, Tohoku University Graduate School of Medicine, Japan. Electronic address: tomish1988@gmail.com.
  • Tateda M; Department of Otorhinolaryngology, Head & Neck Surgery, National Sencai Medical Center, Japan.
  • Oshima H; Department of Otorhinolaryngology, Head & Neck Surgery, National Sencai Medical Center, Japan.
  • Sawada A; Department of Otorhinolaryngology, Head & Neck Surgery, National Sencai Medical Center, Japan.
  • Oka N; Department of Pathology, National Sendai Medical Center, Japan.
  • Suzuki H; Department of Pathology, National Sendai Medical Center, Japan.
  • Hashimoto S; Department of Otorhinolaryngology, Head & Neck Surgery, National Sencai Medical Center, Japan.
Auris Nasus Larynx ; 46(6): 907-911, 2019 Dec.
Article en En | MEDLINE | ID: mdl-30473272
The present article discusses the first reported case of adenoid cystic carcinoma (ACC) metastasis from a submandibular gland to the larynx. Both treatments of distant metastasis of ACC and secondary laryngeal tumor are challenging. Despite its slow progression, ACC is associated with high rates of local recurrence, distant metastasis, and poor prognosis. Patients with secondary laryngeal cancer often have other concurrent metastatic lesions. Therefore, treatment selection should consider the biological behavior of the tumor and characteristics of the laryngeal lesion, along with the general condition and quality of life of the patient. The patient (55-year-old female) had a history of ACC of the right submandibular gland, removed surgically 9 years prior to the present consultation. Follow-up showed multiple pulmonary metastases. The patient complained of dysphonia lasting 3 months. Following the diagnosis of ACC metastasis to the larynx (supraglottic) and a neck lymph node via biopsy, we performed partial laryngectomy, left neck dissection, and tracheotomy. Histopathological examination showed an increase in the tumor grade over time. Two months after discharge, there was no obvious local recurrence or increase in lung metastasis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Glándula Submandibular / Neoplasias Laríngeas / Carcinoma Adenoide Quístico / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Aspecto: Patient_preference Límite: Female / Humans / Middle aged Idioma: En Revista: Auris Nasus Larynx Año: 2019 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Glándula Submandibular / Neoplasias Laríngeas / Carcinoma Adenoide Quístico / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Aspecto: Patient_preference Límite: Female / Humans / Middle aged Idioma: En Revista: Auris Nasus Larynx Año: 2019 Tipo del documento: Article Pais de publicación: Países Bajos