Synthesis and biological evaluation of new pyrazolone Schiff bases as monoamine oxidase and cholinesterase inhibitors.

Tok, Fatih; Koçyigit-Kaymakçioglu, Bedia; Saglik, Begüm Nurpelin; Levent, Serkan; Özkay, Yusuf; Kaplancikli, Zafer Asim

Tok, Fatih; Koçyigit-Kaymakçioglu, Bedia; Saglik, Begüm Nurpelin; Levent, Serkan; Özkay, Yusuf; Kaplancikli, Zafer Asim.

Afiliación

Tok F; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Marmara University, Istanbul, Turkey.
Koçyigit-Kaymakçioglu B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Marmara University, Istanbul, Turkey.
Saglik BN; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey; Doping and Narcotic Compounds Analysis Laboratory, Faculty of Pharmacy, Anadolu Universty, Eskisehir, Turkey.
Levent S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey; Doping and Narcotic Compounds Analysis Laboratory, Faculty of Pharmacy, Anadolu Universty, Eskisehir, Turkey.
Özkay Y; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey; Doping and Narcotic Compounds Analysis Laboratory, Faculty of Pharmacy, Anadolu Universty, Eskisehir, Turkey. Electronic address: yozkay@anadolu.edu.tr.
Kaplancikli ZA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey.

Bioorg Chem ; 84: 41-50, 2019 03.

Article en En | MEDLINE | ID: mdl-30481645

Asunto(s)

Inhibidores de la Colinesterasa/farmacología; Inhibidores de la Monoaminooxidasa/farmacología; Pirazolonas/farmacología; Inhibidores de la Colinesterasa/síntesis química; Inhibidores de la Colinesterasa/química; Relación Dosis-Respuesta a Droga; Humanos; Simulación del Acoplamiento Molecular; Estructura Molecular; Inhibidores de la Monoaminooxidasa/síntesis química; Inhibidores de la Monoaminooxidasa/química; Pirazolonas/síntesis química; Pirazolonas/química; Bases de Schiff/síntesis química; Bases de Schiff/química; Bases de Schiff/farmacología; Relación Estructura-Actividad

Palabras clave

Acetylcholinesterase; Butyrylcholinesterase; Docking; Monoamine oxidase A; Monoamine oxidase B; Schiff base

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de la Colinesterasa / Pirazolonas / Inhibidores de la Monoaminooxidasa Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2019 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos

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