Dietary factors and risk of gout and hyperuricemia: a meta-analysis and systematic review.
Asia Pac J Clin Nutr
; 27(6): 1344-1356, 2018.
Article
en En
| MEDLINE
| ID: mdl-30485934
ABSTRACT
BACKGROUND AND OBJECTIVES:
To evaluate the associations of dietary factors and the risk of gout and hyperuricemia. METHODS AND STUDYDESIGN:
PubMed and Embase databases were searched from inception to June 2017 for eligible studies. Nineteen prospective cohort or cross-sectional studies with adequate sample sizes are included, all involving red meat, seafoods, alcohol, fructose, dairy products, soy foods, high-purine vegetables and coffee.RESULTS:
Meta-analysis revealed several dietary associations with gout risk red meat OR 1.29 (95% CI 1.16-1.44); seafoods OR 1.31 (95% CI 1.01-1.68); alcohol OR 2.58 (95% CI 1.81-3.66); fructose OR 2.14 (95% CI 1.65- 2.78); dairy products OR 0.56 (95% CI 0.44-0.70); soy foods OR 0.85 (95% CI 0.76-0.96); high-purine vegetables OR 0.86 (95% CI 0.75-0.98); coffee OR 0.47 (95% CI 0.37-0.59).Dietary association with hyperuricemia risk (red meat OR 1.24 (95% CI 1.04-1.48); seafoods OR 1.47 (95% CI 1.16-1.86); alcohol OR 2.06 (95% CI 1.60-2.67); fructose OR 1.85 (95% CI 1.66-2.07); dairy products OR 0.50 (95% CI 0.37-0.66); soy foods OR 0.70 (95% CI 0.56-0.88); high-purine vegetables ingestion OR 1.10 (95% CI 0.88-1.39), P=0.39; coffeeOR0.76 in men (95% CI 0.55-1.06), OR 1.58 in women (95% CI 1.16-2.16).CONCLUSION:
The risk of hyperuricemia and gout is positively correlated with the intake of red meat, seafoods, alcohol or fructose, and negatively with dairy products or soy foods. High-purine vegetables showed no association with hyperuricemia, but negative association with gout. Coffee intake is negatively associated with gout risk, whereas it may be associated with increased hyperuricemia risk in women but decreased risk in men.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hiperuricemia
/
Dieta
/
Gota
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prevalence_studies
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Risk_factors_studies
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Systematic_reviews
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Asia Pac J Clin Nutr
Asunto de la revista:
CIENCIAS DA NUTRICAO
Año:
2018
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
CHINA
/
CN
/
REPUBLIC OF CHINA