Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases.

Ohmichi, Takuma; Mitsuhashi, Masato; Tatebe, Harutsugu; Kasai, Takashi; Ali El-Agnaf, Omar M; Tokuda, Takahiko

Ohmichi, Takuma; Mitsuhashi, Masato; Tatebe, Harutsugu; Kasai, Takashi; Ali El-Agnaf, Omar M; Tokuda, Takahiko.

Afiliación

Ohmichi T; Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan. Electronic address: t-omichi@koto.kpu-m.ac.jp.
Mitsuhashi M; NanoSomiX, Inc., Irvine, CA, 92618, USA. Electronic address: mmitsuhashi@nanosomix.com.
Tatebe H; Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan; Department of Zaitaku (Homecare) Medicine, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan. Electronic address: tatebe@koto.kpu-m.ac.jp.
Kasai T; Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan. Electronic address: kasaita@koto.kpu-m.ac.jp.
Ali El-Agnaf OM; Neurological Disorders Research Center, Qatar Biomedical Research Institute (QBRI), Qatar Foundation, PO Box 5825, Doha, Qatar; Life Sciences Division, College of Science and Engineering, Hamad Bin Khalifa University (HBKU), Qatar Foundation, PO Box 5825, Doha, Qatar. Electronic address: oelagnaf@hb
Tokuda T; Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan; Department of Molecular Pathobiology of Brain Diseases, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan. Electronic address: ttokuda@koto.kpu-m.ac.jp.

Parkinsonism Relat Disord ; 61: 82-87, 2019 04.

Article en En | MEDLINE | ID: mdl-30502924

Asunto(s)

Astrocitos/metabolismo; Biomarcadores/metabolismo; Exosomas/metabolismo; Atrofia de Múltiples Sistemas/metabolismo; Neuronas/metabolismo; Oligodendroglía/metabolismo; Enfermedad de Parkinson/metabolismo; Parálisis Supranuclear Progresiva/metabolismo; Adulto; Anciano; Anciano de 80 o más Años; Estudios de Casos y Controles; Ensayo de Inmunoadsorción Enzimática; Transportador 1 de Aminoácidos Excitadores/metabolismo; Vesículas Extracelulares/metabolismo; Femenino; Proteínas Ligadas a GPI/metabolismo; Humanos; Masculino; Persona de Mediana Edad; Proteínas de la Mielina/metabolismo; Proteína 25 Asociada a Sinaptosomas/metabolismo; Tetraspanina 28

Palabras clave

Astrocyte-derived exosome; Neuron-derived exosome; Oligodendrocyte-derived exosome; Parkinson's and related diseases; Plasma biomarker

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Parálisis Supranuclear Progresiva / Biomarcadores / Oligodendroglía / Astrocitos / Atrofia de Múltiples Sistemas / Exosomas / Neuronas Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Parkinsonism Relat Disord Asunto de la revista: NEUROLOGIA Año: 2019 Tipo del documento: Article

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