Selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression.
Arch Womens Ment Health
; 22(3): 431-435, 2019 06.
Article
en En
| MEDLINE
| ID: mdl-30506371
ABSTRACT
The effect of perinatal selective serotonin reuptake inhibitors (SSRIs) on brain-derived neurotrophic factor (BDNF) and S100 calcium binding protein B (S100B) has not been investigated. Using a cohort of 86 pregnant women, we found that SSRIs significantly increase BDNF levels in late pregnancy and that S100B, but not BDNF, is associated with maternal depression in SSRI-treated women only. This shows that serum S100B could be a unique biomarker to determine efficacy of SSRIs during gestation.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Inhibidores Selectivos de la Recaptación de Serotonina
/
Factor Neurotrófico Derivado del Encéfalo
/
Depresión
/
Subunidad beta de la Proteína de Unión al Calcio S100
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Arch Womens Ment Health
Asunto de la revista:
PSICOLOGIA
/
SAUDE DA MULHER
Año:
2019
Tipo del documento:
Article
País de afiliación:
Francia