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Basophils trigger emphysema development in a murine model of COPD through IL-4-mediated generation of MMP-12-producing macrophages.
Shibata, Sho; Miyake, Kensuke; Tateishi, Tomoya; Yoshikawa, Soichiro; Yamanishi, Yoshinori; Miyazaki, Yasunari; Inase, Naohiko; Karasuyama, Hajime.
Afiliación
  • Shibata S; Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
  • Miyake K; Department of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
  • Tateishi T; Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
  • Yoshikawa S; Department of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
  • Yamanishi Y; Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
  • Miyazaki Y; Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
  • Inase N; Department of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
  • Karasuyama H; Department of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.
Proc Natl Acad Sci U S A ; 115(51): 13057-13062, 2018 12 18.
Article en En | MEDLINE | ID: mdl-30510003
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfisema Pulmonar / Basófilos / Interleucina-4 / Macrófagos Alveolares / Enfermedad Pulmonar Obstructiva Crónica / Metaloproteinasa 12 de la Matriz / Macrófagos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfisema Pulmonar / Basófilos / Interleucina-4 / Macrófagos Alveolares / Enfermedad Pulmonar Obstructiva Crónica / Metaloproteinasa 12 de la Matriz / Macrófagos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article País de afiliación: Japón