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DHS (trans-4,4'-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2).
Chen, Chi-Wei; Li, Yongming; Hu, Shuya; Zhou, Wei; Meng, Yunxiao; Li, Zongzhu; Zhang, Yi; Sun, Jing; Bo, Zhou; DePamphilis, Melvin L; Yen, Yun; Han, Zhiyong; Zhu, Wenge.
Afiliación
  • Chen CW; Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
  • Li Y; GW Cancer Center, The George Washington University, Washington, DC, USA.
  • Hu S; Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
  • Zhou W; College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
  • Meng Y; City of Hope National Medical Center, Duarte, CA, USA.
  • Li Z; Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
  • Zhang Y; GW Cancer Center, The George Washington University, Washington, DC, USA.
  • Sun J; Department of Colorectal Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Bo Z; Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
  • DePamphilis ML; GW Cancer Center, The George Washington University, Washington, DC, USA.
  • Yen Y; Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
  • Han Z; GW Cancer Center, The George Washington University, Washington, DC, USA.
  • Zhu W; Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Oncogene ; 38(13): 2364-2379, 2019 03.
Article en En | MEDLINE | ID: mdl-30518875
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ribonucleótido Reductasas / Estilbenos / Proliferación Celular / Replicación del ADN / Neoplasias Límite: Animals / Female / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ribonucleótido Reductasas / Estilbenos / Proliferación Celular / Replicación del ADN / Neoplasias Límite: Animals / Female / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido