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Phytotoxicity reduction of the mercury chloride effect by natural products from Eugenia jambolana Lam.: A new strategy against the toxic metal pollution.
Sobral-Souza, Celestina E; Silva, Ana R P; Leite, Nadghia F; Rocha, Janaina E; Sousa, Amanda K; Costa, José G M; Menezes, Irwin R A; Cunha, Francisco A B; Rolim, Larissa A; Coutinho, Henrique D M.
Afiliación
  • Sobral-Souza CE; Laboratório de Microbiologia e Biologia Molecular, Universidade Regional do Cariri, Rua Cel. Antonio Luis 1161, Pimenta, 63105-000 Crato, CE, Brazil.
  • Silva ARP; Laboratório de Microbiologia e Biologia Molecular, Universidade Regional do Cariri, Rua Cel. Antonio Luis 1161, Pimenta, 63105-000 Crato, CE, Brazil.
  • Leite NF; Laboratório de Microbiologia e Biologia Molecular, Universidade Regional do Cariri, Rua Cel. Antonio Luis 1161, Pimenta, 63105-000 Crato, CE, Brazil.
  • Rocha JE; Laboratório de Microbiologia e Biologia Molecular, Universidade Regional do Cariri, Rua Cel. Antonio Luis 1161, Pimenta, 63105-000 Crato, CE, Brazil.
  • Sousa AK; Laboratório de Microbiologia e Biologia Molecular, Universidade Regional do Cariri, Rua Cel. Antonio Luis 1161, Pimenta, 63105-000 Crato, CE, Brazil.
  • Costa JGM; Laboratório de Pesquisa de Produtos Naturais, Universidade Regional do Cariri, Crato, CE, Brazil.
  • Menezes IRA; Laboratório de Farmacologia e Química Molecular, Universidade Regional do Cariri, Crato, CE, Brazil.
  • Cunha FAB; Laboratório de Microbiologia e Biologia Molecular, Universidade Regional do Cariri, Rua Cel. Antonio Luis 1161, Pimenta, 63105-000 Crato, CE, Brazil.
  • Rolim LA; Central de Análises de Fármacos, Medicamentos e Alimentos, Universidade Federal do Vale do São Francisco, Petrolina, PE, Brazil.
  • Coutinho HDM; Laboratório de Microbiologia e Biologia Molecular, Universidade Regional do Cariri, Rua Cel. Antonio Luis 1161, Pimenta, 63105-000 Crato, CE, Brazil. Electronic address: hdmcoutinho@urca.br.
Ecotoxicol Environ Saf ; 170: 461-467, 2019 Apr 15.
Article en En | MEDLINE | ID: mdl-30553924
The objective of this work was to evaluate the antioxidant, metal chelating and cytoprotective activity of the Eugenia jambolana Lam. extract, as well as of its flavonoid and tannic fractions, against the action of Mercury Chloride (HgCl2). Flavonoids were quantified and an LC-MS chromatographic analysis was performed to identify secondary metabolites. Fe2+ and Fe3+ chelation tests and antioxidant activity were carried out using the FRAP method. Microbiological tests were performed by microdilution to determine the Minimum Inhibitory Concentration (MIC). From these results the Minimum Bactericidal (MBC) and Minimum Fungicide Concentration (MFC) were evaluated. The allelopathy and cytoprotection assays were performed using eukaryotic and prokaryotic models. The results revealed the presence of phenolic acids and flavonoids in the E. jambolana extract and fractions. The sub-allelopathic concentration (64 µg/mL) was used and the results demonstrated the E. jambolana potential cytoprotective effect against mercury chloride.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Productos Biológicos / Syzygium / Cloruro de Mercurio Idioma: En Revista: Ecotoxicol Environ Saf Año: 2019 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Productos Biológicos / Syzygium / Cloruro de Mercurio Idioma: En Revista: Ecotoxicol Environ Saf Año: 2019 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos