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A Divergent Hepatitis D-Like Agent in Birds.
Wille, Michelle; Netter, Hans J; Littlejohn, Margaret; Yuen, Lilly; Shi, Mang; Eden, John-Sebastian; Klaassen, Marcel; Holmes, Edward C; Hurt, Aeron C.
Afiliación
  • Wille M; WHO Collaborating Centre for Reference and Research on Influenza, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia. michelle.wille@influenzacentre.org.
  • Netter HJ; Molecular Research and Development, Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia. Hans.Netter@mh.org.au.
  • Littlejohn M; Molecular Research and Development, Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia. Margaret.Littlejohn@vidrl.org.au.
  • Yuen L; Molecular Research and Development, Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia. Lilly.Yuen@vidrl.org.au.
  • Shi M; Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia. Mang.Shi@sydney.edu.au.
  • Eden JS; Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia. js.eden@sydney.edu.au.
  • Klaassen M; Centre for Integrative Ecology, Deakin University, Geelong, VIC 3220, Australia. Marcel.Klaassen@deakin.edu.au.
  • Holmes EC; Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia. Edward.Holmes@sydney.edu.au.
  • Hurt AC; WHO Collaborating Centre for Reference and Research on Influenza, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia. Aeron.Hurt@influenzacentre.org.
Viruses ; 10(12)2018 12 17.
Article en En | MEDLINE | ID: mdl-30562970
ABSTRACT
Hepatitis delta virus (HDV) is currently only found in humans and is a satellite virus that depends on hepatitis B virus (HBV) envelope proteins for assembly, release, and entry. Using meta-transcriptomics, we identified the genome of a novel HDV-like agent in ducks. Sequence analysis revealed secondary structures that were shared with HDV, including self-complementarity and ribozyme features. The predicted viral protein shares 32% amino acid similarity to the small delta antigen of HDV and comprises a divergent phylogenetic lineage. The discovery of an avian HDV-like agent has important implications for the understanding of the origins of HDV and sub-viral agents.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de las Aves / Hepatitis D / Virus de la Hepatitis Delta / Patos Límite: Animals País/Región como asunto: Oceania Idioma: En Revista: Viruses Año: 2018 Tipo del documento: Article País de afiliación: Australia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de las Aves / Hepatitis D / Virus de la Hepatitis Delta / Patos Límite: Animals País/Región como asunto: Oceania Idioma: En Revista: Viruses Año: 2018 Tipo del documento: Article País de afiliación: Australia