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Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models.
Lowery, Caitlin D; Dowless, Michele; Renschler, Matthew; Blosser, Wayne; VanWye, Alle B; Stephens, Jennifer R; Iversen, Philip W; Lin, Aimee Bence; Beckmann, Richard P; Krytska, Kateryna; Cole, Kristina A; Maris, John M; Hawkins, Douglas S; Rubin, Brian P; Kurmasheva, Raushan T; Houghton, Peter J; Gorlick, Richard; Kolb, E Anders; Kang, Min H; Reynolds, C Patrick; Erickson, Stephen W; Teicher, Beverly A; Smith, Malcolm A; Stancato, Louis F.
Afiliación
  • Lowery CD; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
  • Dowless M; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
  • Renschler M; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
  • Blosser W; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
  • VanWye AB; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
  • Stephens JR; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
  • Iversen PW; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
  • Lin AB; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
  • Beckmann RP; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana.
  • Krytska K; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Cole KA; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Maris JM; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Hawkins DS; Division of Hematology/Oncology, Seattle Children's Hospital, Seattle, Washington.
  • Rubin BP; Departments of Pathology and Cancer Biology, Robert J Tomsich Pathology and Laboratory Medicine Institute and Cleveland Clinic, Cleveland, Ohio.
  • Kurmasheva RT; Greehey Children's Cancer Research Institute, San Antonio, Texas.
  • Houghton PJ; Greehey Children's Cancer Research Institute, San Antonio, Texas.
  • Gorlick R; MD Anderson Cancer Center, Houston, Texas.
  • Kolb EA; Nemours Center for Cancer and Blood Disorders, Wilmington, Delaware.
  • Kang MH; Texas Tech University Health Sciences Center, Lubbock, Texas.
  • Reynolds CP; Texas Tech University Health Sciences Center, Lubbock, Texas.
  • Erickson SW; RTI International, Research Triangle Park, North Carolina.
  • Teicher BA; National Cancer Institute, Bethesda, Maryland.
  • Smith MA; National Cancer Institute, Bethesda, Maryland.
  • Stancato LF; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana. stancato_louis@lilly.com.
Clin Cancer Res ; 25(7): 2278-2289, 2019 04 01.
Article en En | MEDLINE | ID: mdl-30563935
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazinas / Pirazoles / Inhibidores de Proteínas Quinasas / Quinasa 1 Reguladora del Ciclo Celular (Checkpoint 1) / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Child / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazinas / Pirazoles / Inhibidores de Proteínas Quinasas / Quinasa 1 Reguladora del Ciclo Celular (Checkpoint 1) / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Child / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos