Whole-Body Vibration Training Increases Myocardial Salvage Against Acute Ischemia in Adult Male Rats.
Arq Bras Cardiol
; 112(1): 32-37, 2019 01.
Article
en En, Pt
| MEDLINE
| ID: mdl-30570068
ABSTRACT
BACKGROUND:
Whole body vibration training (WBV) is a new training program, which is safe and effective. It can be followed by the public. However, data on the safety and efficacy of vibration on myocardial ischemia reperfusion (IR) injury are lacking.OBJECTIVE:
To examine the effect of WBV on the tolerance of the myocardium to acute IR injury in an experimental rat model.METHODS:
Twenty-four male Wistar rats were divided into control and vibration groups. Vibration training consisted of vertical sinusoidal whole body vibration for 30 min per day, 6 days per week, for 1 or 3 weeks (WBV1 and WBV3 groups, respectively). All the rats were submitted to myocardial IR injury. Myocardial infarct size and ischemia-induced arrhythmias were assessed. Differences between variables were considered significant when p < 0.05.RESULTS:
No differences were observed between the groups regarding the baseline hemodynamic parameters. Infarct size was smaller in the experimental group (control, 47 ± 2%; WBV1, 39 ± 2%; WBV3, 37 ± 2%; p < 0.05, vs. control). Vibration produced a significant decrease in the number and duration of ventricular tachycardia (VT) episodes compared to the control value. All ventricular fibrillation (VF) episodes in the vibration groups were self-limited, while 33% of the rats in the control group died due to irreversible VF (p = 0.02).CONCLUSION:
The data showed that vibration training significantly increased cardiac tolerance to IR injury in rats, as evidenced by reduction in the infarct size and cardiac arrhythmias, and by facilitating spontaneous defibrillation.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Condicionamiento Físico Animal
/
Vibración
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Daño por Reperfusión Miocárdica
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Infarto del Miocardio
Tipo de estudio:
Etiology_studies
/
Evaluation_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Animals
Idioma:
En
/
Pt
Revista:
Arq Bras Cardiol
Año:
2019
Tipo del documento:
Article