Validation of a modified QuEChERS method for the analysis of organochlorine pesticides in fatty biological tissues using two-dimensional gas chromatography.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1105: 85-92, 2019 Jan 15.
Article
en En
| MEDLINE
| ID: mdl-30576889
The monitoring of organic contaminants in the environment has gained tremendous traction in recent times, however, little attention has focused on the development of appropriate methods for the analysis of biological tissues from key sentinel species. In this study, a rapid, low-cost method is presented for the analysis of organochlorine pesticides (OCPs) in fatty biological tissues using a modified QuEChERS (Quick, Easy, Cheap, Efficient, Rugged and Safe) approach. The adapted extraction procedure is tested on biological samples of varying fat content, including fish muscle tissue and two previously untested matrices; coral and adipose tissue. Residue analyses were conducted by two-dimensional gas chromatography-time-of-flight mass spectrometry (GCxGC-TOF-MS). The method was fully validated through the evaluation of recoveries, limits of detection, linearity and precision. Mean recoveries (nâ¯=â¯3) for all 18 target compounds ranged between 69 and 102% across all matrices, with relative standard deviations (RSD) <10% in most cases. Limits of detection (LOD) ranged from 0.1 to 2.0â¯ngâ¯g-1. The method was successfully applied to the analysis of real samples collected from iSimangaliso Wetland Park World Heritage Site, South Africa.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Residuos de Plaguicidas
/
Hidrocarburos Clorados
/
Cromatografía de Gases y Espectrometría de Masas
/
Músculos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
J Chromatogr B Analyt Technol Biomed Life Sci
Asunto de la revista:
ENGENHARIA BIOMEDICA
Año:
2019
Tipo del documento:
Article
Pais de publicación:
Países Bajos