Stabilization of apo &#945;-lactalbumin by binding of epigallocatechin-3-gallate: Experimental and molecular dynamics study.

Radibratovic, Milica; Al-Hanish, Ayah; Minic, Simeon; Radomirovic, Mirjana; Milcic, Milos; Stanic-Vucinic, Dragana; Cirkovic Velickovic, Tanja

Stabilization of apo α-lactalbumin by binding of epigallocatechin-3-gallate: Experimental and molecular dynamics study.

Radibratovic, Milica; Al-Hanish, Ayah; Minic, Simeon; Radomirovic, Mirjana; Milcic, Milos; Stanic-Vucinic, Dragana; Cirkovic Velickovic, Tanja.

Afiliación

Radibratovic M; Center for Chemistry - Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade, Serbia.
Al-Hanish A; Center of Excellence for Molecular Food Sciences & Department of Biochemistry, University of Belgrade - Faculty of Chemistry, Belgrade, Serbia.
Minic S; Center of Excellence for Molecular Food Sciences & Department of Biochemistry, University of Belgrade - Faculty of Chemistry, Belgrade, Serbia.
Radomirovic M; Center of Excellence for Molecular Food Sciences & Department of Biochemistry, University of Belgrade - Faculty of Chemistry, Belgrade, Serbia.
Milcic M; Center for Computational Chemistry and Bioinformatics & Department of Inorganic Chemistry, University of Belgrade - Faculty of Chemistry, Belgrade, Serbia.
Stanic-Vucinic D; Center of Excellence for Molecular Food Sciences & Department of Biochemistry, University of Belgrade - Faculty of Chemistry, Belgrade, Serbia.
Cirkovic Velickovic T; Center of Excellence for Molecular Food Sciences & Department of Biochemistry, University of Belgrade - Faculty of Chemistry, Belgrade, Serbia; Ghent University Global Campus, Yeonsu-gu, Incheon, South Korea; Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium. Electronic address

Food Chem ; 278: 388-395, 2019 Apr 25.

Article en En | MEDLINE | ID: mdl-30583389

Asunto(s)

Apoproteínas/química; Catequina/análogos & derivados; Lactalbúmina/química; Simulación de Dinámica Molecular; Animales; Apoproteínas/metabolismo; Sitios de Unión; Calcio/química; Catequina/química; Catequina/metabolismo; Concentración de Iones de Hidrógeno; Lactalbúmina/metabolismo; Unión Proteica; Desnaturalización Proteica; Estabilidad Proteica; Estructura Secundaria de Proteína; Espectrometría de Fluorescencia

Palabras clave

Apo α-lactalbumin; Epigallocatechin-3-gallate; Fluorescence quenching; Molecular dynamics simulation; Noncovalent interactions; Protein stability

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apoproteínas / Catequina / Simulación de Dinámica Molecular / Lactalbúmina Límite: Animals Idioma: En Revista: Food Chem Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido

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