Evaluation of Different Colorless Nail Polishes Used as Supportive Care in Patients with Cancer in Terms of Photoprotective Efficacy and Water Resistance.

ABSTRACT

Background: In patients undergoing chemotherapy, the application of nail polish and/or a colorless base coat is recommended in order to prevent the adverse effects that can occur on the nails throughout treatment. Objective: In this study, the photoprotective effects of different clear nail polishes were examined. Methods: Twelve commercially available, colorless nail products were tested in vitro. Two layers of the product were applied, as recommended to patients, on polymethyl methacrylate (PMMA) plates. The efficacy indices in the ultraviolet (UV) B sun protection factor (SPF) and UVA regions were then determined with an integrated sphere spectophotometer. Water resistance was also evaluated. Results: Certain colorless nail polishes, such as Mavala 6 Osaka or CC bleaching base with silicium for yellow nails (Vitry), can provide a significant level of photoprotection, with SPF values of above 150. All of the products tested, with the exception of the aqueous gel, are water resistant. Conclusion: Colorless nail polish applied in two layers provides UV protection for the nails in the UVB and UVA ranges. The nature of the vehicle influences the photoprotective efficiency and the water resistance.