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Epilepsy in Children: From Diagnosis to Treatment with Focus on Emergency.
Minardi, Carmelo; Minacapelli, Roberta; Valastro, Pietro; Vasile, Francesco; Pitino, Sofia; Pavone, Piero; Astuto, Marinella; Murabito, Paolo.
Afiliación
  • Minardi C; Department of Anesthesiology, AOU Policlinico-Vittorio Emanuele, University of Catania Via S. Sofia, 78, 95123 Catania, Italy. minardi.carmelo@virgilio.it.
  • Minacapelli R; Department of Anesthesiology, AOU Policlinico-Vittorio Emanuele, University of Catania Via S. Sofia, 78, 95123 Catania, Italy. robertaminacapelli@gmail.com.
  • Valastro P; Department of Anesthesiology, AOU Policlinico-Vittorio Emanuele, University of Catania Via S. Sofia, 78, 95123 Catania, Italy. valastrop87@gmail.com.
  • Vasile F; Department of Anesthesiology, AOU Policlinico-Vittorio Emanuele, University of Catania Via S. Sofia, 78, 95123 Catania, Italy. Frankie.Vas@hotmail.it.
  • Pitino S; Department of Anesthesiology, AOU Policlinico-Vittorio Emanuele, University of Catania Via S. Sofia, 78, 95123 Catania, Italy. sofp85@gmail.com.
  • Pavone P; Department of Pediatrics, AOU Policlinico-Vittorio Emanuele, University of Catania Via S. Sofia, 78, 95123 Catania, Italy. ppavone@unict.it.
  • Astuto M; Department of Anesthesiology, AOU Policlinico-Vittorio Emanuele, University of Catania Via S. Sofia, 78, 95123 Catania, Italy. astmar@tiscali.it.
  • Murabito P; Department of Anesthesiology, AOU Policlinico-Vittorio Emanuele, University of Catania Via S. Sofia, 78, 95123 Catania, Italy. paolomurabito@tiscali.it.
J Clin Med ; 8(1)2019 Jan 02.
Article en En | MEDLINE | ID: mdl-30609770
ABSTRACT
Seizures are defined as a transient occurrence of signs and symptoms due to the abnormal, excessive, or synchronous neuronal activity in the brain characterized by abrupt and involuntary skeletal muscle activity. An early diagnosis, treatment, and specific medical support must be performed to prevent Status Epilepticus (SE). Seizure onset, especially in the child population, is related to specific risk factors like positive family history, fever, infections, neurological comorbidity, premature birth, mother's alcohol abuse, and smoking in pregnancy. Early death risk in children without neurological comorbidity is similar to the general population. Diagnosis is generally based on the identification of continuous or recurrent seizures but Electroencephalogram (EEG) evaluation could be useful if SE condition is suspected. The main goal of therapy is to counteract the pathological mechanism which occurs in SE before neural cells are irreversibly damaged. According to the latest International Guidelines and Recommendations of seizure related diseases, a schematic and multi-stage pharmacological and diagnostic approach is proposed especially in the management of SE and its related causes in children. First measures should focus on early and appropriate drugs administration at adequate dosage, airway management, monitoring vital signs, Pediatric Intensive Care Unit (PICU) admission, and management of parent anxiety.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies / Risk_factors_studies / Screening_studies Idioma: En Revista: J Clin Med Año: 2019 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies / Risk_factors_studies / Screening_studies Idioma: En Revista: J Clin Med Año: 2019 Tipo del documento: Article País de afiliación: Italia
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