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Tumor targeting with DGEA peptide ligands: a new aromatic peptide amphiphile for imaging cancers.
Zhan, Fu-Kai; Liu, Jyun-Cheng; Cheng, Bill; Liu, Yen-Chu; Lai, Tsung-Sheng; Lin, Hsin-Chieh; Yeh, Mei-Yu.
Afiliación
  • Zhan FK; Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, 300, Taiwan. hclin45@nctu.edu.tw.
  • Liu JC; Department of Chemistry, Chung Yuan Christian University, Taoyuan, 320, Taiwan. myyeh@cycu.edu.tw.
  • Cheng B; Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, 300, Taiwan. hclin45@nctu.edu.tw.
  • Liu YC; Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, 300, Taiwan. hclin45@nctu.edu.tw.
  • Lai TS; Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, 300, Taiwan. hclin45@nctu.edu.tw.
  • Lin HC; Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, 300, Taiwan. hclin45@nctu.edu.tw.
  • Yeh MY; Department of Chemistry, Chung Yuan Christian University, Taoyuan, 320, Taiwan. myyeh@cycu.edu.tw.
Chem Commun (Camb) ; 55(8): 1060-1063, 2019 Jan 25.
Article en En | MEDLINE | ID: mdl-30617356
ABSTRACT
We report a novel fluorescent bioprobe, tetraphenylethylene-Phe-Asp-Gly-Glu-Ala (TPE-FDGEA), and its self-assembly behavior, photophysical properties, and biocompatibility. The hydrogelator TPE-FDGEA exhibited aggregation-induced emission characteristics, which facilitated imaging of PC-3 human prostate cancer cells, thereby demonstrating the utility of such fluorescent probes for specific labeling of target cells in vitro.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oligopéptidos / Neoplasias de la Próstata / Estilbenos / Imagen Óptica / Colorantes Fluorescentes Límite: Humans / Male Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Taiwán

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oligopéptidos / Neoplasias de la Próstata / Estilbenos / Imagen Óptica / Colorantes Fluorescentes Límite: Humans / Male Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Taiwán