Novel redispersible nanosuspensions stabilized by co-processed nanocrystalline cellulose-sodium carboxymethyl starch for enhancing dissolution and oral bioavailability of baicalin.

Xie, Jin; Luo, Yijing; Liu, Yang; Ma, Yueqin; Yue, Pengfei; Yang, Ming

Xie, Jin; Luo, Yijing; Liu, Yang; Ma, Yueqin; Yue, Pengfei; Yang, Ming.

Afiliación

Xie J; Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China, ypfpharm@126.com.
Luo Y; Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China, ypfpharm@126.com.
Liu Y; Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China, ypfpharm@126.com.
Ma Y; Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China, ypfpharm@126.com.
Yue P; Department of Pharmaceutics, 94th Hospital of People's Liberation Army, Nanchang, China.
Yang M; Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China, ypfpharm@126.com.

Int J Nanomedicine ; 14: 353-369, 2019.

Article en En | MEDLINE | ID: mdl-30655668

Asunto(s)

Celulosa/química; Flavonoides/farmacología; Nanopartículas/química; Almidón/análogos & derivados; Suspensiones/química; Administración Oral; Animales; Disponibilidad Biológica; Rastreo Diferencial de Calorimetría; Elasticidad; Flavonoides/farmacocinética; Masculino; Tamaño de la Partícula; Ratas Wistar; Reología; Solubilidad; Almidón/química; Electricidad Estática; Viscosidad

Palabras clave

Pickering nanosuspensions; nanocrystalline cellulose; nanocrystals; oral bioavailability; solid particles stabilizer

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Almidón / Suspensiones / Flavonoides / Celulosa / Nanopartículas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int J Nanomedicine Año: 2019 Tipo del documento: Article Pais de publicación: Nueva Zelanda

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