Tetrahydroisoquinoline CXCR4 Antagonists Adopt a Hybrid Binding Mode within the Peptide Subpocket of the CXCR4 Receptor.

Katzman, Brooke M; Cox, Bryan D; Prosser, Anthony R; Alcaraz, Ana A; Murat, Brigitte; Héroux, Madeleine; Tebben, Andrew; Zhang, Yong; Schroeder, Gretchen M; Snyder, James P; Wilson, Lawrence J; Liotta, Dennis C

Katzman, Brooke M; Cox, Bryan D; Prosser, Anthony R; Alcaraz, Ana A; Murat, Brigitte; Héroux, Madeleine; Tebben, Andrew; Zhang, Yong; Schroeder, Gretchen M; Snyder, James P; Wilson, Lawrence J; Liotta, Dennis C.

Afiliación

Katzman BM; Department of Chemistry, Emory University, 1521 Dickey Drive, Atlanta, Georgia 30322, United States.
Cox BD; Department of Chemistry, Emory University, 1521 Dickey Drive, Atlanta, Georgia 30322, United States.
Prosser AR; Department of Chemistry, Emory University, 1521 Dickey Drive, Atlanta, Georgia 30322, United States.
Alcaraz AA; Department of Chemistry, Emory University, 1521 Dickey Drive, Atlanta, Georgia 30322, United States.
Murat B; Medicinal Chemistry platform, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec H3C 3J7, Canada.
Héroux M; Medicinal Chemistry platform, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec H3C 3J7, Canada.
Tebben A; Bristol-Myers Squibb R&D, US Route 206 and Province Line Road, Princeton, New Jersey 08543-4000, United States.
Zhang Y; Bristol-Myers Squibb R&D, US Route 206 and Province Line Road, Princeton, New Jersey 08543-4000, United States.
Schroeder GM; Bristol-Myers Squibb R&D, US Route 206 and Province Line Road, Princeton, New Jersey 08543-4000, United States.
Snyder JP; Department of Chemistry, Emory University, 1521 Dickey Drive, Atlanta, Georgia 30322, United States.
Wilson LJ; Department of Chemistry, Emory University, 1521 Dickey Drive, Atlanta, Georgia 30322, United States.
Liotta DC; Department of Chemistry, Emory University, 1521 Dickey Drive, Atlanta, Georgia 30322, United States.

ACS Med Chem Lett ; 10(1): 67-73, 2019 Jan 10.

Article en En | MEDLINE | ID: mdl-30655949

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACS Med Chem Lett Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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