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Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.
Oshima, Tsuyoshi; Niwa, Yoshimi; Kuwata, Keiko; Srivastava, Ashutosh; Hyoda, Tomoko; Tsuchiya, Yoshiki; Kumagai, Megumi; Tsuyuguchi, Masato; Tamaru, Teruya; Sugiyama, Akiko; Ono, Natsuko; Zolboot, Norjin; Aikawa, Yoshiki; Oishi, Shunsuke; Nonami, Atsushi; Arai, Fumio; Hagihara, Shinya; Yamaguchi, Junichiro; Tama, Florence; Kunisaki, Yuya; Yagita, Kazuhiro; Ikeda, Masaaki; Kinoshita, Takayoshi; Kay, Steve A; Itami, Kenichiro; Hirota, Tsuyoshi.
Afiliación
  • Oshima T; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Niwa Y; Department of Chemistry, Graduate School of Science, Nagoya University, Nagoya 464-8601, Japan.
  • Kuwata K; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Srivastava A; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Hyoda T; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Tsuchiya Y; Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
  • Kumagai M; Department of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
  • Tsuyuguchi M; Department of Physiology, Faculty of Medicine, Saitama Medical University, Saitama 350-0495, Japan.
  • Tamaru T; Graduate School of Science, Osaka Prefecture University, Osaka 599-8531, Japan.
  • Sugiyama A; Department of Physiology and Advanced Research Center for Medical Science, Toho University School of Medicine, Tokyo 143-8540, Japan.
  • Ono N; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Zolboot N; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Aikawa Y; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Oishi S; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Nonami A; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Arai F; Center for Advanced Medical Innovation, Kyushu University, Fukuoka 812-8582, Japan.
  • Hagihara S; Department of Stem Cell Biology and Medicine/Cancer Stem Cell Research, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan.
  • Yamaguchi J; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Tama F; Department of Chemistry, Graduate School of Science, Nagoya University, Nagoya 464-8601, Japan.
  • Kunisaki Y; PRESTO, JST, Nagoya 464-8601, Japan.
  • Yagita K; Department of Applied Chemistry, Waseda University, Tokyo 169-8555, Japan.
  • Ikeda M; Institute of Transformative Bio-Molecules, Nagoya University, Nagoya 464-8601, Japan.
  • Kinoshita T; Department of Physics, Graduate School of Science, Nagoya University, Nagoya 464-8601, Japan, and RIKEN Center for Computational Science, Kobe 650-0047, Japan.
  • Kay SA; Department of Stem Cell Biology and Medicine/Cancer Stem Cell Research, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan.
  • Itami K; Department of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
  • Hirota T; Department of Physiology, Faculty of Medicine, Saitama Medical University, Saitama 350-0495, Japan.
Sci Adv ; 5(1): eaau9060, 2019 01.
Article en En | MEDLINE | ID: mdl-30746467
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Carcinoma de Células Renales / Ritmo Circadiano / Proliferación Celular / Relojes Circadianos / Neoplasias Renales Límite: Animals / Humans Idioma: En Revista: Sci Adv Año: 2019 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Carcinoma de Células Renales / Ritmo Circadiano / Proliferación Celular / Relojes Circadianos / Neoplasias Renales Límite: Animals / Humans Idioma: En Revista: Sci Adv Año: 2019 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos