Small cell lung cancers made from scratch.
J Exp Med
; 216(3): 476-478, 2019 03 04.
Article
en En
| MEDLINE
| ID: mdl-30760489
ABSTRACT
In this issue of JEM, Chen et al. (https//doi.org/10.1084/jem.20181155) describe a new approach for the transformation of human pluripotent embryonic stem cells (hESCs) into neuroendocrine (NE) tumors of the lung closely resembling human small cell lung cancer (SCLC). Another recent study uses a different method to transform fully differentiated normal human cells into high-grade NE tumors (Park et al. 2018. Science https//doi.org/10.1126/science.aat5749). These approaches and their models provide important new resources for developing diagnostic, preventative, and therapeutic approaches for high-grade NE tumors.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Carcinoma Pulmonar de Células Pequeñas
/
Células Madre Embrionarias Humanas
/
Neoplasias Pulmonares
Límite:
Humans
Idioma:
En
Revista:
J Exp Med
Año:
2019
Tipo del documento:
Article