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Choosing a Mouse Model of Venous Thrombosis.
Diaz, Jose A; Saha, Prakash; Cooley, Brian; Palmer, Olivia R; Grover, Steven P; Mackman, Nigel; Wakefield, Thomas W; Henke, Peter K; Smith, Alberto; Lal, Brajesh K.
Afiliación
  • Diaz JA; From the Department of Surgery, Vascular Surgery, University of Michigan, Ann Arbor (J.A.D., O.R.P., T.W.W., P.K.H.).
  • Saha P; Academic Department of Vascular Surgery, King's College London, UK (P.S., A.S.).
  • Cooley B; Department of Medicine, Division of Hematology/Oncology, University of North Carolina at Chapel Hill (B.C., S.P.G., N.M.).
  • Palmer OR; From the Department of Surgery, Vascular Surgery, University of Michigan, Ann Arbor (J.A.D., O.R.P., T.W.W., P.K.H.).
  • Grover SP; Department of Medicine, Division of Hematology/Oncology, University of North Carolina at Chapel Hill (B.C., S.P.G., N.M.).
  • Mackman N; Department of Medicine, Division of Hematology/Oncology, University of North Carolina at Chapel Hill (B.C., S.P.G., N.M.).
  • Wakefield TW; From the Department of Surgery, Vascular Surgery, University of Michigan, Ann Arbor (J.A.D., O.R.P., T.W.W., P.K.H.).
  • Henke PK; From the Department of Surgery, Vascular Surgery, University of Michigan, Ann Arbor (J.A.D., O.R.P., T.W.W., P.K.H.).
  • Smith A; Academic Department of Vascular Surgery, King's College London, UK (P.S., A.S.).
  • Lal BK; Department of Surgery, University of Maryland, College Park (B.K.L.).
Arterioscler Thromb Vasc Biol ; 39(3): 311-318, 2019 03.
Article en En | MEDLINE | ID: mdl-30786739
Murine models are widely used valuable tools to study deep vein thrombosis. Leading experts in venous thrombosis research came together through the American Venous Forum to develop a consensus on maximizing the utility and application of available mouse models of venous thrombosis. In this work, we provide an algorithm for model selection, with discussion of the advantages, disadvantages, and applications of the main mouse models of venous thrombosis. Additionally, we provide a detailed surgical description of the models with guidelines to validate surgical technique.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trombosis de la Vena / Modelos Animales de Enfermedad / Ratones Tipo de estudio: Etiology_studies / Guideline / Prognostic_studies / Qualitative_research Límite: Animals Idioma: En Revista: Arterioscler Thromb Vasc Biol Asunto de la revista: ANGIOLOGIA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trombosis de la Vena / Modelos Animales de Enfermedad / Ratones Tipo de estudio: Etiology_studies / Guideline / Prognostic_studies / Qualitative_research Límite: Animals Idioma: En Revista: Arterioscler Thromb Vasc Biol Asunto de la revista: ANGIOLOGIA Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos