A hydrodynamic-stochastic model of chemotactic ciliated microorganisms.
Eur Phys J E Soft Matter
; 42(2): 20, 2019 Feb 21.
Article
en En
| MEDLINE
| ID: mdl-30788619
Biological systems like ciliated microorganisms are capable of responding to the external chemical gradients, a process known as chemotaxis. In this process, the internal signaling network of the microorganism is triggered due to binding of the chemoattractant molecules with the receptors on the surface of the body. This can alter the activity at the surface of the microorganism. We study the chemotaxis of ciliated microorganisms using the chiral squirmer model, a spherical body with a surface slip velocity. In the presence of a chemical gradient, the coefficients of the slip velocity get modified resulting in a change in the path followed by the body. We observe that the strength of the gradient is not the only parameter which controls the dynamics of the body but also the adaptation time plays a very significant role in the success of chemotaxis. The trajectory of the body is smooth if we ignore the discreteness in the ligand-receptor binding which is stochastic in nature. In the presence of the latter, the path is not only irregular but the whole dynamics of the body changes. We calculate the mean first passage time, by varying the strength of the chemical gradient and the adaptation time, to determine the success rate of chemotaxis.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quimiotaxis
/
Procesos Estocásticos
/
Hidrodinámica
/
Modelos Biológicos
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Eur Phys J E Soft Matter
Asunto de la revista:
BIOFISICA
Año:
2019
Tipo del documento:
Article
País de afiliación:
India
Pais de publicación:
Francia