Exploration of inositol 1,4,5-trisphosphate (IP<sub>3</sub>) regulated dynamics of N-terminal domain of IP<sub>3</sub> receptor reveals early phase molecular events during receptor activation.

Chandran, Aneesh; Chee, Xavier; Prole, David L; Rahman, Taufiq

Exploration of inositol 1,4,5-trisphosphate (IP₃) regulated dynamics of N-terminal domain of IP₃ receptor reveals early phase molecular events during receptor activation.

Chandran, Aneesh; Chee, Xavier; Prole, David L; Rahman, Taufiq.

Afiliación

Chandran A; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD, Cambridge, UK. aneeshc@iisc.ac.in.
Chee X; Molecular Biophysics Unit, Indian Institute of Science, 560 012, Bangalore, India. aneeshc@iisc.ac.in.
Prole DL; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD, Cambridge, UK.
Rahman T; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD, Cambridge, UK.

Sci Rep ; 9(1): 2454, 2019 02 21.

Article en En | MEDLINE | ID: mdl-30792485

Asunto(s)

Receptores de Inositol 1,4,5-Trifosfato/química; Receptores de Inositol 1,4,5-Trifosfato/metabolismo; Inositol 1,4,5-Trifosfato/metabolismo; Regulación Alostérica; Animales; Calcio/metabolismo; Enlace de Hidrógeno; Ratones; Modelos Moleculares; Simulación de Dinámica Molecular; Unión Proteica; Conformación Proteica

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inositol 1,4,5-Trifosfato / Receptores de Inositol 1,4,5-Trifosfato Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido

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