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Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
Sakornsakolpat, Phuwanat; Prokopenko, Dmitry; Lamontagne, Maxime; Reeve, Nicola F; Guyatt, Anna L; Jackson, Victoria E; Shrine, Nick; Qiao, Dandi; Bartz, Traci M; Kim, Deog Kyeom; Lee, Mi Kyeong; Latourelle, Jeanne C; Li, Xingnan; Morrow, Jarrett D; Obeidat, Ma'en; Wyss, Annah B; Bakke, Per; Barr, R Graham; Beaty, Terri H; Belinsky, Steven A; Brusselle, Guy G; Crapo, James D; de Jong, Kim; DeMeo, Dawn L; Fingerlin, Tasha E; Gharib, Sina A; Gulsvik, Amund; Hall, Ian P; Hokanson, John E; Kim, Woo Jin; Lomas, David A; London, Stephanie J; Meyers, Deborah A; O'Connor, George T; Rennard, Stephen I; Schwartz, David A; Sliwinski, Pawel; Sparrow, David; Strachan, David P; Tal-Singer, Ruth; Tesfaigzi, Yohannes; Vestbo, Jørgen; Vonk, Judith M; Yim, Jae-Joon; Zhou, Xiaobo; Bossé, Yohan; Manichaikul, Ani; Lahousse, Lies; Silverman, Edwin K; Boezen, H Marike.
Afiliación
  • Sakornsakolpat P; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Prokopenko D; Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
  • Lamontagne M; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Reeve NF; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
  • Guyatt AL; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Quebec, Canada.
  • Jackson VE; Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester, UK.
  • Shrine N; Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester, UK.
  • Qiao D; Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester, UK.
  • Bartz TM; Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester, UK.
  • Kim DK; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Lee MK; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
  • Latourelle JC; Department of Medicine, University of Washington, Seattle, WA, USA.
  • Li X; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Morrow JD; Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, Seoul, South Korea.
  • Obeidat M; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Raleigh, NC, USA.
  • Wyss AB; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
  • Bakke P; Department of Medicine, University of Arizona, Tucson, AZ, USA.
  • Barr RG; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Beaty TH; University of British Columbia Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
  • Belinsky SA; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Raleigh, NC, USA.
  • Brusselle GG; Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Crapo JD; Department of Medicine, College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
  • de Jong K; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
  • DeMeo DL; Lovelace Respiratory Research Institute, Albuquerque, NM, USA.
  • Fingerlin TE; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Gharib SA; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
  • Gulsvik A; Department of Respiratory Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Hall IP; Division of Pulmonary and Critical Care Medicine, Department of Medicine, National Jewish Health, Denver, CO, USA.
  • Hokanson JE; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, the Netherlands.
  • Kim WJ; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, the Netherlands.
  • Lomas DA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • London SJ; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Meyers DA; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, USA.
  • O'Connor GT; Department of Biostatistics and Informatics, University of Colorado Denver, Aurora, CO, USA.
  • Rennard SI; Computational Medicine Core, Center for Lung Biology, UW Medicine Sleep Center, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Schwartz DA; Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Sliwinski P; Division of Respiratory Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
  • Sparrow D; National Institute for Health Research Nottingham Biomedical Research Centre, Nottingham, UK.
  • Strachan DP; Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Tal-Singer R; Department of Internal Medicine and Environmental Health Center, School of Medicine, Kangwon National University, Chuncheon, South Korea.
  • Tesfaigzi Y; UCL Respiratory, University College London, London, UK.
  • Vestbo J; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Raleigh, NC, USA.
  • Vonk JM; Department of Medicine, University of Arizona, Tucson, AZ, USA.
  • Yim JJ; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA.
  • Zhou X; Pulmonary Center, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Bossé Y; Pulmonary, Critical Care, Sleep and Allergy Division, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
  • Manichaikul A; Clinical Discovery Unit, AstraZeneca, Cambridge, UK.
  • Lahousse L; Department of Medicine, School of Medicine, University of Colorado Denver, Aurora, CO, USA.
  • Silverman EK; Department of Immunology, School of Medicine, University of Colorado Denver, Aurora, CO, USA.
  • Boezen HM; 2nd Department of Respiratory Medicine, Institute of Tuberculosis and Lung Diseases, Warsaw, Poland.
Nat Genet ; 51(3): 494-505, 2019 03.
Article en En | MEDLINE | ID: mdl-30804561
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Predisposición Genética a la Enfermedad / Enfermedad Pulmonar Obstructiva Crónica Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Predisposición Genética a la Enfermedad / Enfermedad Pulmonar Obstructiva Crónica Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos