Five cases of Plasmodium vivax malaria treated with artemisinin derivatives: the advantages of a unified approach to treatment.
Infection
; 47(4): 655-659, 2019 Aug.
Article
en En
| MEDLINE
| ID: mdl-30809760
ABSTRACT
OBJECTIVES:
In endemic countries with a high level of chloroquine resistance, Plasmodium vivax malaria is associated with high morbidity and mortality. In these areas, the dihydroartemisinin-piperaquine combination resulted in clinical response, a more rapid clearance of parasitaemia, compared to chloroquine therapies, and reduction of recrudescence or reinfection.METHODS:
We describe five cases of Plasmodium vivax malaria in returning travelers treated with dihydroartemisinin-piperaquine.RESULTS:
All patients showed the early parasite clearance and no side effects. Our preliminary results suggest that the dihydroartemisinin-piperaquine combination is effective and safe even in imported cases.CONCLUSIONS:
A unified treatment policy using the artemisinin combination therapy should be adopted even in non-endemic countries and larger studies are underway to support this strategy.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Primaquina
/
Malaria Vivax
/
Artemisininas
/
Antimaláricos
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Infection
Año:
2019
Tipo del documento:
Article
País de afiliación:
Italia