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Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy.
Logtenberg, Meike E W; Jansen, J H Marco; Raaben, Matthijs; Toebes, Mireille; Franke, Katka; Brandsma, Arianne M; Matlung, Hanke L; Fauster, Astrid; Gomez-Eerland, Raquel; Bakker, Noor A M; van der Schot, Simone; Marijt, Koen A; Verdoes, Martijn; Haanen, John B A G; van den Berg, Joost H; Neefjes, Jacques; van den Berg, Timo K; Brummelkamp, Thijn R; Leusen, Jeanette H W; Scheeren, Ferenc A; Schumacher, Ton N.
Afiliación
  • Logtenberg MEW; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Jansen JHM; Laboratory for Translational Immunology, UMC Utrecht, Utrecht, The Netherlands.
  • Raaben M; Division of Biochemistry, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Toebes M; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Franke K; Department of Blood Cell Research, Sanquin Research, Landsteiner Laboratory, and Department of Molecular Cell Biology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
  • Brandsma AM; Laboratory for Translational Immunology, UMC Utrecht, Utrecht, The Netherlands.
  • Matlung HL; Department of Blood Cell Research, Sanquin Research, Landsteiner Laboratory, and Department of Molecular Cell Biology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
  • Fauster A; Division of Biochemistry, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Gomez-Eerland R; Division of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Bakker NAM; Division of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • van der Schot S; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Marijt KA; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.
  • Verdoes M; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Haanen JBAG; Institute for Chemical Immunology, Amsterdam, The Netherlands.
  • van den Berg JH; Division of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Neefjes J; Division of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • van den Berg TK; Institute for Chemical Immunology, Amsterdam, The Netherlands.
  • Brummelkamp TR; Department of Cell and Chemical Biology, Oncode Institute, Leiden University Medical Center, Leiden, The Netherlands.
  • Leusen JHW; Department of Blood Cell Research, Sanquin Research, Landsteiner Laboratory, and Department of Molecular Cell Biology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
  • Scheeren FA; Division of Biochemistry, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Schumacher TN; Laboratory for Translational Immunology, UMC Utrecht, Utrecht, The Netherlands.
Nat Med ; 25(4): 612-619, 2019 04.
Article en En | MEDLINE | ID: mdl-30833751
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Inmunológicos / Antígenos de Diferenciación / Aminoaciltransferasas / Antígeno CD47 / Inmunoterapia / Neoplasias Límite: Animals / Humans Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Inmunológicos / Antígenos de Diferenciación / Aminoaciltransferasas / Antígeno CD47 / Inmunoterapia / Neoplasias Límite: Animals / Humans Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos