Fecal calprotectin and fecal indole predict outcome of fecal microbiota transplantation in subjects with recurrent Clostridium difficile infection.

Hibbard, J; Jiang, Z-D; DuPont, H L

Hibbard, J; Jiang, Z-D; DuPont, H L.

Afiliación

Hibbard J; Ohio Wesleyan University, USA. Electronic address: Herbert.L.DuPont@uth.tmc.edu.
Jiang ZD; Kelsey Research Foundation, USA; University of Texas School of Public Health, USA.
DuPont HL; Kelsey Research Foundation, USA; University of Texas School of Public Health, USA; University of Texas McGovern Medical School, USA; Baylor College of Medicine, USA.

Anaerobe ; 56: 102-105, 2019 Apr.

Article en En | MEDLINE | ID: mdl-30851429

ABSTRACT

ABSTRACT

Fecal calprotectin and indole were studied in 134 subjects with recurrent CDI before and after FMT. Reduced fecal calprotectin (pâ¯=â¯0.0353, 95% CI 0.1305-0.1439) and rising levels of indole (pâ¯<â¯0.0001, 95% CIâ¯<â¯0.0001-0.0003) predicted successful treatment. A ratio of recal calprotectin/indole may provide prognostic value for FMT (pâ¯=â¯0.0004, 95% CI 0.22-0.87).

Asunto(s)

Infecciones por Clostridium/terapia; Trasplante de Microbiota Fecal; Heces/química; Indoles/análisis; Complejo de Antígeno L1 de Leucocito/análisis; Adulto; Anciano; Anciano de 80 o más Años; Femenino; Humanos; Masculino; Persona de Mediana Edad; Recurrencia; Resultado del Tratamiento; Adulto Joven

Palabras clave

C. difficile infection; Calprotectin; FMT; IBD; Indole

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Clostridium / Complejo de Antígeno L1 de Leucocito / Heces / Trasplante de Microbiota Fecal / Indoles Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Anaerobe Año: 2019 Tipo del documento: Article

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