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Oncogenic EP300 can be targeted with inhibitors of aldo-keto reductases.
Mahmud, Zimam; Asaduzzaman, Muhammad; Kumar, Uttom; Masrour, Nahal; Jugov, Roman; Coombes, R Charles; Shousha, Sami; Hu, Yunhui; Lam, Eric W-F; Yagüe, Ernesto.
Afiliación
  • Mahmud Z; Division of Cancer, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.
  • Asaduzzaman M; Division of Cancer, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.
  • Kumar U; Division of Cancer, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.
  • Masrour N; Division of Cancer, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.
  • Jugov R; Division of Cancer, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.
  • Coombes RC; Division of Cancer, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.
  • Shousha S; Centre for Pathology, Department of Medicine, Imperial College Faculty of Medicine, Charing Cross Hospital, Fulham Palace Rd, London W6 8RF, United Kingdom.
  • Hu Y; Department of Breast Cancer, China Tianjin Breast Cancer Prevention, Treatment and Research Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Huan Hu Xi Road, Ti Yuan Bei, He xi District, Tianjin 300060, PR China.
  • Lam EW; Division of Cancer, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.
  • Yagüe E; Division of Cancer, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom. Electronic address: ernesto.yague@imperial.ac.uk.
Biochem Pharmacol ; 163: 391-403, 2019 05.
Article en En | MEDLINE | ID: mdl-30862505
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Regulación Neoplásica de la Expresión Génica / Proteína p300 Asociada a E1A / Aldo-Ceto Reductasas Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Biochem Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Regulación Neoplásica de la Expresión Génica / Proteína p300 Asociada a E1A / Aldo-Ceto Reductasas Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Biochem Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido