Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes.

Bugliani, M; Mossuto, S; Grano, F; Suleiman, M; Marselli, L; Boggi, U; De Simone, P; Eizirik, D L; Cnop, M; Marchetti, P; De Tata, V

Bugliani, M; Mossuto, S; Grano, F; Suleiman, M; Marselli, L; Boggi, U; De Simone, P; Eizirik, D L; Cnop, M; Marchetti, P; De Tata, V.

Afiliación

Bugliani M; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Mossuto S; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Grano F; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Suleiman M; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Marselli L; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Boggi U; Department of Surgical Pathology, Medicine, Molecular and Critical Area, University of Pisa, Pisa, Italy.
De Simone P; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Eizirik DL; Medical Faculty, ULB Center for Diabetes Research, Université Libre de Bruxelles, Brussels, Belgium.
Cnop M; Medical Faculty, ULB Center for Diabetes Research, Université Libre de Bruxelles, Brussels, Belgium.
Marchetti P; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
De Tata V; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Front Endocrinol (Lausanne) ; 10: 52, 2019.

Article en En | MEDLINE | ID: mdl-30863363

Palabras clave

ER stress; autophagy; beta cell dysfunction; human islets; insulin secretion; type 2 diabetes

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Endocrinol (Lausanne) Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza

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