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Acute increases in O-GlcNAc indirectly impair mitochondrial bioenergetics through dysregulation of LonP1-mediated mitochondrial protein complex turnover.
Wright, JaLessa N; Benavides, Gloria A; Johnson, Michelle S; Wani, Willayat; Ouyang, Xiaosen; Zou, Luyun; Collins, Helen E; Zhang, Jianhua; Darley-Usmar, Victor; Chatham, John C.
Afiliación
  • Wright JN; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama , Birmingham, Alabama.
  • Benavides GA; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama , Birmingham, Alabama.
  • Johnson MS; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama , Birmingham, Alabama.
  • Wani W; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama , Birmingham, Alabama.
  • Ouyang X; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama , Birmingham, Alabama.
  • Zou L; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama , Birmingham, Alabama.
  • Collins HE; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama , Birmingham, Alabama.
  • Zhang J; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama , Birmingham, Alabama.
  • Darley-Usmar V; Birmingham VA Medical Center, University of Alabama , Birmingham, Alabama.
  • Chatham JC; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama , Birmingham, Alabama.
Am J Physiol Cell Physiol ; 316(6): C862-C875, 2019 06 01.
Article en En | MEDLINE | ID: mdl-30865517

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetilglucosamina / Beta-N-Acetilhexosaminidasas / Regulación hacia Abajo / Proteínas Mitocondriales / Proteasas ATP-Dependientes / Metabolismo Energético / Mitocondrias Límite: Humans Idioma: En Revista: Am J Physiol Cell Physiol Asunto de la revista: FISIOLOGIA Año: 2019 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetilglucosamina / Beta-N-Acetilhexosaminidasas / Regulación hacia Abajo / Proteínas Mitocondriales / Proteasas ATP-Dependientes / Metabolismo Energético / Mitocondrias Límite: Humans Idioma: En Revista: Am J Physiol Cell Physiol Asunto de la revista: FISIOLOGIA Año: 2019 Tipo del documento: Article