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KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival.
Vendramini, Elena; Bomben, Riccardo; Pozzo, Federico; Benedetti, Dania; Bittolo, Tamara; Rossi, Francesca Maria; Dal Bo, Michele; Rabe, Kari G; Pozzato, Gabriele; Zaja, Francesco; Chiarenza, Annalisa; Di Raimondo, Francesco; Braggio, Esteban; Parikh, Sameer A; Kay, Neil E; Shanafelt, Tait D; Del Poeta, Giovanni; Gattei, Valter; Zucchetto, Antonella.
Afiliación
  • Vendramini E; Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy.
  • Bomben R; Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy.
  • Pozzo F; Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy.
  • Benedetti D; Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy.
  • Bittolo T; Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy.
  • Rossi FM; Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy.
  • Dal Bo M; Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy.
  • Rabe KG; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
  • Pozzato G; Department of Internal Medicine and Haematology, Maggiore General Hospital, University of Trieste, Trieste, Italy.
  • Zaja F; Department of Internal Medicine and Haematology, Maggiore General Hospital, University of Trieste, Trieste, Italy.
  • Chiarenza A; Division of Hematology, Ferrarotto Hospital, Catania, Italy.
  • Di Raimondo F; Division of Hematology, Ferrarotto Hospital, Catania, Italy.
  • Braggio E; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
  • Parikh SA; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
  • Kay NE; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
  • Shanafelt TD; Department of Hematology/Oncology, Stanford University, Stanford, CA, USA.
  • Del Poeta G; Division of Hematology, S. Eugenio Hospital and University of Tor Vergata, Rome, Italy.
  • Gattei V; Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy. vgattei@cro.it.
  • Zucchetto A; Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy. zucchetto.soecs@cro.it.
Leukemia ; 33(8): 2111-2115, 2019 08.
Article en En | MEDLINE | ID: mdl-30872781
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trisomía / Cromosomas Humanos Par 12 / Leucemia Linfocítica Crónica de Células B / Proteínas Proto-Oncogénicas p21(ras) / Proteínas Proto-Oncogénicas B-raf / GTP Fosfohidrolasas / Proteínas de la Membrana / Mutación Tipo de estudio: Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trisomía / Cromosomas Humanos Par 12 / Leucemia Linfocítica Crónica de Células B / Proteínas Proto-Oncogénicas p21(ras) / Proteínas Proto-Oncogénicas B-raf / GTP Fosfohidrolasas / Proteínas de la Membrana / Mutación Tipo de estudio: Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Italia