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The effect of LILRB1 but not LILRA3 gene polymorphism in immunopathology of ankylosing spondylitis-A parallel to KIR genes.
Majorczyk, Edyta; Wisniewski, Andrzej; Zon-Giebel, Aleksandra; Chlebicki, Arkadiusz; Wiland, Piotr; Kusnierczyk, Piotr.
Afiliación
  • Majorczyk E; Department of Clinical Immunology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
  • Wisniewski A; Department of Biochemistry and Physiology, Faculty of Physical Education and Physiotherapy, Institute of Physiotherapy, Opole University of Technology, Opole, Poland.
  • Zon-Giebel A; Department of Clinical Immunology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
  • Chlebicki A; Silesian Centre for Rheumatology, Rehabilitation and Disability Prevention, Ustron, Poland.
  • Wiland P; Department and Clinic of Rheumatology and Internal Medicine, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland.
  • Kusnierczyk P; Department and Clinic of Rheumatology and Internal Medicine, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland.
Int J Immunogenet ; 46(3): 146-151, 2019 Jun.
Article en En | MEDLINE | ID: mdl-30892832
ABSTRACT
LILR and KIR receptors recognize HLA-B27 and may influence immune response in ankylosing spondylitis (AS) development. Purpose of the study was to analyse LILRB1/LILRA3 polymorphisms in AS. We observed a possible protective effect of the T allele of LILRB1 rs1061680T>C and no association with insertion/deletion polymorphisms of LILRA3 with AS.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Espondilitis Anquilosante / Receptores Inmunológicos / Antígenos CD / Receptores KIR / Receptor Leucocitario Tipo Inmunoglobulina B1 Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Immunogenet Asunto de la revista: ALERGIA E IMUNOLOGIA / GENETICA Año: 2019 Tipo del documento: Article País de afiliación: Polonia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Espondilitis Anquilosante / Receptores Inmunológicos / Antígenos CD / Receptores KIR / Receptor Leucocitario Tipo Inmunoglobulina B1 Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Immunogenet Asunto de la revista: ALERGIA E IMUNOLOGIA / GENETICA Año: 2019 Tipo del documento: Article País de afiliación: Polonia