A Stable Large Animal Model for Dural Defect Repair with Biomaterials and Regenerative Medicine.

Guo, Jinhai; He, Shukun; Tu, Yunhu; Zhang, Yi; Wang, Zhule; Wu, Shizhou; Huang, Fuguo; He, Wei; Li, Xiaoming; Xie, Huiqi

Guo, Jinhai; He, Shukun; Tu, Yunhu; Zhang, Yi; Wang, Zhule; Wu, Shizhou; Huang, Fuguo; He, Wei; Li, Xiaoming; Xie, Huiqi.

Afiliación

Guo J; 1 Laboratory of Stem Cell and Tissue Engineering, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan, China.
He S; 2 Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Tu Y; 3 Department of Orthopedics, The First People's Hospital of Jintang County (The Jintang Hospital of West China Hospital, Sichuan University), Chengdu, Sichuan, China.
Zhang Y; 1 Laboratory of Stem Cell and Tissue Engineering, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan, China.
Wang Z; 2 Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wu S; 4 Department of Aesthetic Plastic Surgery, BRAVOU Aesthetic Plastic Hospital, Chengdu, Sichuan, China.
Huang F; 1 Laboratory of Stem Cell and Tissue Engineering, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan, China.
He W; 1 Laboratory of Stem Cell and Tissue Engineering, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan, China.
Li X; 2 Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xie H; 1 Laboratory of Stem Cell and Tissue Engineering, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan, China.

Tissue Eng Part C Methods ; 25(6): 315-323, 2019 06.

Article en En | MEDLINE | ID: mdl-30919756

RESUMEN

IMPACT STATEMENT: Using biomaterials and regenerative medicine to repair tissue defects has been a very hot research field, during which the development of stable large animal models with appropriate biotechnology is crucial. Recently, more and more researchers are paying attention to dural defect repair. However, the lack of widely recognized stable large animal models has seriously affected the related further research. In this study, a stable large animal dural defect model is developed exactly for the first time. Therefore, the article would attract considerable attention and be highly cited after publication.

Asunto(s)

Materiales Biocompatibles/farmacología; Duramadre/patología; Medicina Regenerativa; Cicatrización de Heridas/efectos de los fármacos; Animales; Antígenos CD/metabolismo; Antígenos de Diferenciación Mielomonocítica/metabolismo; Modelos Animales de Enfermedad; Perros; Duramadre/efectos de los fármacos; Femenino; Masculino

Palabras clave

dural defect; large animal model; repair materials; surgical methods

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cicatrización de Heridas / Materiales Biocompatibles / Medicina Regenerativa / Duramadre Límite: Animals Idioma: En Revista: Tissue Eng Part C Methods Asunto de la revista: BIOTECNOLOGIA / HISTOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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