Aberrations in DNA repair pathways in cancer and therapeutic significances.

Motegi, Akira; Masutani, Mitsuko; Yoshioka, Ken-Ichi; Bessho, Tadayoshi

Motegi, Akira; Masutani, Mitsuko; Yoshioka, Ken-Ichi; Bessho, Tadayoshi.

Afiliación

Motegi A; Department of Radiation Genetics, Kyoto University Graduate School of Medicine, Yoshida Konoe, Sakyo-ku, Kyoto 606-8501, Japan.
Masutani M; Department of Frontier Life Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki 852-8588, Japan; Division of Cellular Signaling, Lab of Collaborative Research, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. Elect
Yoshioka KI; Division of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Bessho T; Eppley Institute for Cancer Research and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198 -6805, USA.

Semin Cancer Biol ; 58: 29-46, 2019 10.

Article en En | MEDLINE | ID: mdl-30922960

Asunto(s)

Reparación del ADN/genética; Neoplasias/genética; Animales; Carcinogénesis/genética; Inestabilidad Genómica/genética; Humanos; Mutación/genética

Palabras clave

Homologous recombination repair; Mismatch repair; Nucleotide excision repair; PARP; Synthetic lethality

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reparación del ADN / Neoplasias Límite: Animals / Humans Idioma: En Revista: Semin Cancer Biol Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

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