Indole itself and its novel derivative affect PML cells proliferation via controlling the expression of cell cycle genes.

Noroozi, Mojgan Karimabad; Mahmoodi, Mehd; Jafarzadeh, Abdollah; Darehkordi, Ali; Hajizadeh, Mohammad Reza; Khorramdelazad, Hossein; Sayadi, Ahmad Reza; Falahati-Pour, Soudeh Khanamani; Hassanshahi, Gholamhossein

Noroozi, Mojgan Karimabad; Mahmoodi, Mehd; Jafarzadeh, Abdollah; Darehkordi, Ali; Hajizadeh, Mohammad Reza; Khorramdelazad, Hossein; Sayadi, Ahmad Reza; Falahati-Pour, Soudeh Khanamani; Hassanshahi, Gholamhossein.

Afiliación

Noroozi MK; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Mahmoodi M; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Jafarzadeh A; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Darehkordi A; Department of Chemistry, Faculty of Science, Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran.
Hajizadeh MR; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Khorramdelazad H; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Sayadi AR; Social Determinants of Health Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Falahati-Pour SK; Pistachio Safety Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Hassanshahi G; Molecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Cell Mol Biol (Noisy-le-grand) ; 65(3): 41-47, 2019 Mar 31.

Article en En | MEDLINE | ID: mdl-30942154

Asunto(s)

Proteínas de Ciclo Celular/genética; Regulación Leucémica de la Expresión Génica/efectos de los fármacos; Indoles/farmacología; Leucemia Promielocítica Aguda/genética; Leucemia Promielocítica Aguda/patología; Apoptosis/efectos de los fármacos; Apoptosis/genética; Proteínas de Ciclo Celular/metabolismo; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Humanos; Indoles/química; ARN Mensajero/genética; ARN Mensajero/metabolismo

Palabras clave

C19H15F3N2O; Cancer; Flow cytometry; Gene; Real-time PCR; Western blot.

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Promielocítica Aguda / Regulación Leucémica de la Expresión Génica / Proteínas de Ciclo Celular / Indoles Límite: Humans Idioma: En Revista: Cell Mol Biol (Noisy-le-grand) Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Francia

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