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Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms.
Blauwendraat, Cornelis; Heilbron, Karl; Vallerga, Costanza L; Bandres-Ciga, Sara; von Coelln, Rainer; Pihlstrøm, Lasse; Simón-Sánchez, Javier; Schulte, Claudia; Sharma, Manu; Krohn, Lynne; Siitonen, Ari; Iwaki, Hirotaka; Leonard, Hampton; Noyce, Alastair J; Tan, Manuela; Gibbs, J Raphael; Hernandez, Dena G; Scholz, Sonja W; Jankovic, Joseph; Shulman, Lisa M; Lesage, Suzanne; Corvol, Jean-Christophe; Brice, Alexis; van Hilten, Jacobus J; Marinus, Johan; Eerola-Rautio, Johanna; Tienari, Pentti; Majamaa, Kari; Toft, Mathias; Grosset, Donald G; Gasser, Thomas; Heutink, Peter; Shulman, Joshua M; Wood, Nicolas; Hardy, John; Morris, Huw R; Hinds, David A; Gratten, Jacob; Visscher, Peter M; Gan-Or, Ziv; Nalls, Mike A; Singleton, Andrew B.
Afiliación
  • Blauwendraat C; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
  • Heilbron K; Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.
  • Vallerga CL; 23andMe, Inc., Mountain View, California, USA.
  • Bandres-Ciga S; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia.
  • von Coelln R; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
  • Pihlstrøm L; Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Simón-Sánchez J; Department of Neurology, Oslo University Hospital, Oslo, Norway.
  • Schulte C; Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Sharma M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Krohn L; Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Siitonen A; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Iwaki H; Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tubingen, Germany.
  • Leonard H; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
  • Noyce AJ; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
  • Tan M; Institute of Clinical Medicine, Department of Neurology, University of Oulu, Oulu, Finland.
  • Gibbs JR; Department of Neurology and Medical Research Center, Oulu University Hospital, Oulu, Finland.
  • Hernandez DG; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
  • Scholz SW; The Michael J Fox Foundation for Parkinson's Research, New York, New York, USA.
  • Jankovic J; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
  • Shulman LM; Preventive Neurology Unit, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom.
  • Lesage S; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.
  • Corvol JC; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.
  • Brice A; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
  • van Hilten JJ; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
  • Marinus J; Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.
  • Eerola-Rautio J; Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Tienari P; Inserm U1127, Sorbonne Universités, UPMC Univ Paris 06 UMR S1127, Institut du Cerveau et de la Moelle épinière, ICM, Paris, France.
  • Majamaa K; Inserm U1127, Sorbonne Universités, UPMC Univ Paris 06 UMR S1127, Institut du Cerveau et de la Moelle épinière, ICM, Paris, France.
  • Toft M; Inserm U1127, Sorbonne Universités, UPMC Univ Paris 06 UMR S1127, Institut du Cerveau et de la Moelle épinière, ICM, Paris, France.
  • Grosset DG; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
  • Gasser T; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
  • Shulman JM; Department of Neurology, Helsinki University Hospital, and Molecular Neurology, Research Programs Unit, Biomedicum, University of Helsinki, Helsinki, Finland.
  • Wood N; Department of Neurology, Helsinki University Hospital, and Molecular Neurology, Research Programs Unit, Biomedicum, University of Helsinki, Helsinki, Finland.
  • Hardy J; Institute of Clinical Medicine, Department of Neurology, University of Oulu, Oulu, Finland.
  • Morris HR; Department of Neurology and Medical Research Center, Oulu University Hospital, Oulu, Finland.
  • Hinds DA; Department of Neurology, Oslo University Hospital, Oslo, Norway.
  • Gratten J; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Visscher PM; Department of Neurology, Institute of Neurological Sciences, Queen Elizabeth University Hospital, Glasgow, United Kingdom.
  • Gan-Or Z; Institute of Neuroscience & Psychology, University of Glasgow, Glasgow, United Kingdom.
  • Nalls MA; Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Singleton AB; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
Mov Disord ; 34(6): 866-875, 2019 06.
Article en En | MEDLINE | ID: mdl-30957308
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Edad de Inicio / Alfa-Sinucleína / Sitios Genéticos Tipo de estudio: Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Mov Disord Asunto de la revista: NEUROLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Edad de Inicio / Alfa-Sinucleína / Sitios Genéticos Tipo de estudio: Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Mov Disord Asunto de la revista: NEUROLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos