Comparative cost-effectiveness of immunoassays and FLOTAC for diagnosing Giardia spp. infection in dogs.
Parasit Vectors
; 12(1): 158, 2019 Apr 08.
Article
en En
| MEDLINE
| ID: mdl-30961639
ABSTRACT
BACKGROUND:
Giardia spp. is a protozoan pathogen and is the most common enteric parasite of domestic animals and humans. Assays for detecting infection in fecal samples using direct or indirect examinations are important tools for diagnosing the disease. The objective of the present study was to compare the cost-effectiveness of immunoassays and FLOTAC technique for diagnosing Giardia spp. infection in dogs.RESULTS:
Fecal samples from 80 positive stray dogs were tested for the presence of copro-antigens of Giardia spp. using the direct immunofluorescence assay (IFA), a rapid enzyme-linked immunosorbent assay (ELISA) and the FLOTAC double technique. All methods were performed in accordance with the instructions reported in the original description for each technique. The results showed that ELISA can be run in less time than IFA and almost at the same time of the FLOTAC technique. Among the tests used in this study, FLOTAC had the lowest cost per correct diagnosis, compared with immunoassays.CONCLUSIONS:
The results from this cost-effectiveness analysis, in combination with the sensitivity and specificity of the FLOTAC technique, suggest that the FLOTAC technique can be use in the routine diagnosis of Giardia spp. infection in dogs.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ensayo de Inmunoadsorción Enzimática
/
Giardiasis
/
Técnica del Anticuerpo Fluorescente Directa
/
Enfermedades de los Perros
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
/
Health_economic_evaluation
Límite:
Animals
Idioma:
En
Revista:
Parasit Vectors
Año:
2019
Tipo del documento:
Article
País de afiliación:
Italia