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Bouchardatine suppresses rectal cancer in mice by disrupting its metabolic pathways via activating the SIRT1-PGC-1α-UCP2 axis.
Xu, Yao-Hao; Song, Qin-Qin; Li, Chan; Hu, Yu-Tao; Song, Bing-Bing; Ye, Ji-Ming; Rao, Yong; Huang, Zhi-Shu.
Afiliación
  • Xu YH; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Song QQ; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Li C; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Hu YT; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Song BB; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Ye JM; Lipid Biology and Metabolic Disease Laboratory, School of Health and Biomedical Sciences, RMIT University, Melbourne, VIC, 3083 Australia.
  • Rao Y; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. Electronic address: raoyong0805@126.com.
  • Huang ZS; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Eur J Pharmacol ; 854: 328-337, 2019 Jul 05.
Article en En | MEDLINE | ID: mdl-31028741
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Recto / Alcaloides Indólicos / Sirtuina 1 / Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma / Proteína Desacopladora 2 Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Eur J Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Recto / Alcaloides Indólicos / Sirtuina 1 / Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma / Proteína Desacopladora 2 Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Eur J Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos