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Strong and Sustained Antihypertensive Effect of Small Interfering RNA Targeting Liver Angiotensinogen.
Uijl, Estrellita; Mirabito Colafella, Katrina M; Sun, Yuan; Ren, Liwei; van Veghel, Richard; Garrelds, Ingrid M; de Vries, René; Poglitsch, Marko; Zlatev, Ivan; Kim, Jae B; Hoorn, Ewout J; Foster, Don; Danser, A H Jan.
Afiliación
  • Uijl E; From the Division of Vascular Medicine and Pharmacology (E.U., K.M.M.C., Y.S., L.R., R.v.V., I.M.G., R.d.V., A.H.J.D.), Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
  • Mirabito Colafella KM; Division of Nephrology and Transplantation (E.U., E.J.H.), Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
  • Sun Y; From the Division of Vascular Medicine and Pharmacology (E.U., K.M.M.C., Y.S., L.R., R.v.V., I.M.G., R.d.V., A.H.J.D.), Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
  • Ren L; Cardiovascular Program, Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, VIC, Australia (K.M.M.C.).
  • van Veghel R; From the Division of Vascular Medicine and Pharmacology (E.U., K.M.M.C., Y.S., L.R., R.v.V., I.M.G., R.d.V., A.H.J.D.), Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
  • Garrelds IM; From the Division of Vascular Medicine and Pharmacology (E.U., K.M.M.C., Y.S., L.R., R.v.V., I.M.G., R.d.V., A.H.J.D.), Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
  • de Vries R; From the Division of Vascular Medicine and Pharmacology (E.U., K.M.M.C., Y.S., L.R., R.v.V., I.M.G., R.d.V., A.H.J.D.), Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
  • Poglitsch M; From the Division of Vascular Medicine and Pharmacology (E.U., K.M.M.C., Y.S., L.R., R.v.V., I.M.G., R.d.V., A.H.J.D.), Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
  • Zlatev I; From the Division of Vascular Medicine and Pharmacology (E.U., K.M.M.C., Y.S., L.R., R.v.V., I.M.G., R.d.V., A.H.J.D.), Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
  • Kim JB; Attoquant Diagnostics, Vienna, Austria (M.P.).
  • Hoorn EJ; Alnylam Pharmaceuticals, Cambridge, MA (I.Z., J.B.K., D.F.).
  • Foster D; Alnylam Pharmaceuticals, Cambridge, MA (I.Z., J.B.K., D.F.).
  • Danser AHJ; Division of Nephrology and Transplantation (E.U., E.J.H.), Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
Hypertension ; 73(6): 1249-1257, 2019 06.
Article en En | MEDLINE | ID: mdl-31030610
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presión Sanguínea / Angiotensinógeno / Regulación de la Expresión Génica / ARN Interferente Pequeño / Hipertensión / Hígado Límite: Animals Idioma: En Revista: Hypertension Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presión Sanguínea / Angiotensinógeno / Regulación de la Expresión Génica / ARN Interferente Pequeño / Hipertensión / Hígado Límite: Animals Idioma: En Revista: Hypertension Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos