Mechanism of cognate sequence discrimination by the ETS-family transcription factor ETS-1.

Huang, Kenneth; Xhani, Suela; Albrecht, Amanda V; Ha, Van L T; Esaki, Shingo; Poon, Gregory M K

Huang, Kenneth; Xhani, Suela; Albrecht, Amanda V; Ha, Van L T; Esaki, Shingo; Poon, Gregory M K.

Afiliación

Huang K; From the Department of Chemistry and.
Xhani S; From the Department of Chemistry and.
Albrecht AV; From the Department of Chemistry and.
Ha VLT; From the Department of Chemistry and.
Esaki S; From the Department of Chemistry and.
Poon GMK; From the Department of Chemistry and gpoon@gsu.edu.

J Biol Chem ; 294(25): 9666-9678, 2019 06 21.

Article en En | MEDLINE | ID: mdl-31048376

Asunto(s)

ADN/química; ADN/metabolismo; Proteína Proto-Oncogénica c-ets-1/química; Proteína Proto-Oncogénica c-ets-1/metabolismo; Animales; Secuencia de Bases; Sitios de Unión; Ratones; Modelos Moleculares; Simulación de Dinámica Molecular; Unión Proteica; Conformación Proteica

Palabras clave

DNA binding protein; DNA sequence motif; DNA-binding domain; ETS proto-oncogene 1 transcription factor (ETS1); ETS transcription factor family; allosteric regulation; developmental factor; low-affinity DNA binding; molecular dynamics; suboptimization; transcription enhancer; transcription factor

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Proteína Proto-Oncogénica c-ets-1 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos

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