GATA-1 isoforms differently contribute to the production and compartmentation of reactive oxygen species in the myeloid leukemia cell line K562.

Riccio, Patrizia; Sessa, Raffaele; de Nicola, Sergio; Petruzziello, Fara; Trombetti, Silvia; Menna, Giuseppe; Pepe, Giampiero; Maddalena, Pasquale; Izzo, Paola; Grosso, Michela

Riccio, Patrizia; Sessa, Raffaele; de Nicola, Sergio; Petruzziello, Fara; Trombetti, Silvia; Menna, Giuseppe; Pepe, Giampiero; Maddalena, Pasquale; Izzo, Paola; Grosso, Michela.

Afiliación

Riccio P; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
Sessa R; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
de Nicola S; CNR-SPIN, National Research Council, Institute for Superconductors, Innovative Materials and Devices, Naples, Italy.
Petruzziello F; Pediatric Hematology Unit, Santobono-Pausilipon Hospital, Naples, Italy.
Trombetti S; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.
Menna G; Pediatric Hematology Unit, Santobono-Pausilipon Hospital, Naples, Italy.
Pepe G; CNR-SPIN, National Research Council, Institute for Superconductors, Innovative Materials and Devices, Naples, Italy.
Maddalena P; Department of Physics, University of Naples Federico II, Naples, Italy.
Izzo P; Department of Physics, University of Naples Federico II, Naples, Italy.
Grosso M; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.

J Cell Physiol ; 234(11): 20829-20846, 2019 11.

Article en En | MEDLINE | ID: mdl-31049966

Asunto(s)

Compartimento Celular; Factor de Transcripción GATA1/metabolismo; Leucemia Mieloide/metabolismo; Leucemia Mieloide/patología; Especies Reactivas de Oxígeno/metabolismo; Antioxidantes/metabolismo; Apoptosis/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Grupo Citocromo b/metabolismo; ADN Mitocondrial/metabolismo; Complejo II de Transporte de Electrones/metabolismo; Humanos; Células K562; Oxidación-Reducción; Estrés Oxidativo/efectos de los fármacos; Isoformas de Proteínas/metabolismo; Subunidades de Proteína/metabolismo; Quercetina/farmacología; Succinato Deshidrogenasa/metabolismo

Palabras clave

GATA-1; mitochondria remodeling; myeloid leukemia; oxidative stress; succinate dehydrogenase subunit C (SDHC)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Mieloide / Compartimento Celular / Especies Reactivas de Oxígeno / Factor de Transcripción GATA1 Límite: Humans Idioma: En Revista: J Cell Physiol Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

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