Dynamic extraction coupled on-line to liquid chromatography with a parallel sampling interface-a proof of concept for monitoring extraction kinetics.
Anal Bioanal Chem
; 411(16): 3675-3683, 2019 Jun.
Article
en En
| MEDLINE
| ID: mdl-31062062
ABSTRACT
On-line hyphenation of extraction with chromatography has been explored in several different types of combinations. However, monitoring the complete process of a dynamic, continuous-flow extraction is not possible with any hyphenated system reported so far. The current work demonstrates that this challenging task can be effectively fulfilled by using a parallel sampling interface, which mimics the concept of comprehensive two-dimensional chromatography. In this study, pressurised hot water extraction was coupled on-line with ultra-high-performance liquid chromatography. The set-up was utilised in a kinetic study of dynamic pressurised hot water extraction of curcuminoids from turmeric powder. Compound-specific extraction curves were obtained, which clearly indicated the rate-limiting factors of the extraction processes under different conditions. Additionally, thermal degradation of curcumin during the extraction could also be demonstrated in some of the extractions.
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Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Anal Bioanal Chem
Año:
2019
Tipo del documento:
Article
País de afiliación:
Suecia