Tumor targeted micellar nanocarriers assembled from epipodophyllotoxin-based amphiphiles.
Nanoscale
; 11(19): 9756-9759, 2019 May 16.
Article
en En
| MEDLINE
| ID: mdl-31066425
ABSTRACT
Micelle-forming amphiphilic drug conjugates were synthesized starting from a biologically active epipodophyllotoxin derivative which was covalently inserted in between a hydrophilic PEG unit and a hydrophobic stearyl chain. The epipodophyllotoxin-containing amphiphiles were assembled into the corresponding micelles which were evaluated in vivo for their tumor targeting properties.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Podofilotoxina
/
Portadores de Fármacos
/
Nanopartículas
/
Micelas
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Nanoscale
Año:
2019
Tipo del documento:
Article