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Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8+ T cells and impede CAR T-cell efficacy.
van Bruggen, Jaco A C; Martens, Anne W J; Fraietta, Joseph A; Hofland, Tom; Tonino, Sanne H; Eldering, Eric; Levin, Mark-David; Siska, Peter J; Endstra, Sanne; Rathmell, Jeffrey C; June, Carl H; Porter, David L; Melenhorst, J Joseph; Kater, Arnon P; van der Windt, Gerritje J W.
Afiliación
  • van Bruggen JAC; Department of Hematology, Cancer Center Amsterdam.
  • Martens AWJ; Lymphoma and Myeloma Center Amsterdam, and.
  • Fraietta JA; Department of Experimental Immunology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, University of Amsterdam, The Netherlands.
  • Hofland T; Department of Hematology, Cancer Center Amsterdam.
  • Tonino SH; Lymphoma and Myeloma Center Amsterdam, and.
  • Eldering E; Department of Experimental Immunology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, University of Amsterdam, The Netherlands.
  • Levin MD; Department of Pathology and Laboratory Medicine.
  • Siska PJ; Department of Microbiology.
  • Endstra S; Center for Cellular Immunotherapies, and.
  • Rathmell JC; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • June CH; Department of Hematology, Cancer Center Amsterdam.
  • Porter DL; Lymphoma and Myeloma Center Amsterdam, and.
  • Melenhorst JJ; Department of Experimental Immunology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, University of Amsterdam, The Netherlands.
  • Kater AP; Department of Hematology, Cancer Center Amsterdam.
  • van der Windt GJW; Lymphoma and Myeloma Center Amsterdam, and.
Blood ; 134(1): 44-58, 2019 07 04.
Article en En | MEDLINE | ID: mdl-31076448
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Linfocítica Crónica de Células B / Inmunoterapia Adoptiva / Linfocitos T CD8-positivos / Mitocondrias Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Blood Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Linfocítica Crónica de Células B / Inmunoterapia Adoptiva / Linfocitos T CD8-positivos / Mitocondrias Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Blood Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos