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Dexamethasone changes the pharmacokinetics of amitriptyline and reduces its accumulation in rat brain: The roles of P-gp and cyp3a2.
Wen, Jing; Shen, Yuan; Zhang, Min; Wang, Chao; Xiang, Yalan; Cai, Hualin; Fang, Pingfei; Li, Huande.
Afiliación
  • Wen J; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, PR China; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, PR China.
  • Shen Y; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, PR China; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, PR China.
  • Zhang M; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, PR China; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, PR China.
  • Wang C; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, PR China; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, PR China.
  • Xiang Y; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, PR China; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, PR China.
  • Cai H; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, PR China; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, PR China.
  • Fang P; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, PR China; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, PR China. Electronic address: fangpingfei@csu.edu.cn.
  • Li H; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, PR China; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, PR China.
J Pharmacol Sci ; 140(1): 54-61, 2019 May.
Article en En | MEDLINE | ID: mdl-31105024
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Dexametasona / Barrera Hematoencefálica / Miembro 1 de la Subfamilia B de Casetes de Unión a ATP / Citocromo P-450 CYP3A / Amitriptilina / Antidepresivos Tricíclicos Límite: Animals Idioma: En Revista: J Pharmacol Sci Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article Pais de publicación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Dexametasona / Barrera Hematoencefálica / Miembro 1 de la Subfamilia B de Casetes de Unión a ATP / Citocromo P-450 CYP3A / Amitriptilina / Antidepresivos Tricíclicos Límite: Animals Idioma: En Revista: J Pharmacol Sci Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article Pais de publicación: Japón